Results 121 to 130 of about 11,052,815 (324)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Access Interfaces for Open Archival Information Systems based on the OAI-PMH and the OpenURL Framework for Context-Sensitive Services

open access: yes, 2005
In recent years, a variety of digital repository and archival systems have been developed and adopted. All of these systems aim at hosting a variety of compound digital assets and at providing tools for storing, managing and accessing those assets.
Bekaert, Jeroen, Van de Sompel, Herbert
core   +1 more source

Web Tracking: Mechanisms, Implications, and Defenses [PDF]

open access: yes, 2015
This articles surveys the existing literature on the methods currently used by web services to track the user online as well as their purposes, implications, and possible user's defenses.
Barlet-Ros, Pere   +3 more
core   +2 more sources

Wikidata and Persistent Identifiers

open access: yes, 2016
Presentation on the wikidata service and its relationship to existing and potential future persistent identifiers of relevance to scholarly communications.
openaire   +1 more source

Persistent Identifier Of Instrumentation

open access: yes, 2017
Introduction to the instrument identifier ...
openaire   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Petri net equivalence [PDF]

open access: yes, 1987
Determining whether two Petri nets are equivalent is an interesting problem from both practical and theoretical standpoints. Although it is undecidable in the general case, for many interesting nets the equivalence problem is solvable.
Sidwell, Richard D.
core   +1 more source

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