Results 111 to 120 of about 24,777 (270)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Persistent Identifiers and the Next Generation of Legal Scholarship
This article discusses the importance of the most common persistent identifiers in scholarly communications—the digital object identifier and the ORCID identifier—to legal scholarship. Persistent identifiers help preserve and disseminate academic content
Retteen, Aaron, Hall-Retteen, Malikah
core +1 more source
Using Persistent Identifiers in a research workflow
, 2019 Presentation given by Esther Plomp for the PID NL - A workshop on the use of Persistent Identifiers in the Netherlands on the 20th of November in The Hague, The Netherlands.
Esther Plomp, Esther Plomp (6501731)
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, 2016 Presentation at CESSDA Workshop: Persistent Identification within ...
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Persistent identifiers and their use in digital libraries [PDF]
, 2013 The aim of this thesis is to present persistent identification systems and analysis of the use of persistent identifiers for digital objects on a sample of national digital libraries. The first part is a brief introduction to digital libraries.
Jílková, Marta
core
Implementing Persistent Identifiers
, 2019 Traditionally, organisations have relied on URL hyperlinks to provide interested parties with access to their digitised content via the internet. However, over time, more and more of these hyperlinks are ‘broken’. The URL relies on providing the specific location details for a document.
Hilse, Hans-Werner, Kothe, Jochen
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source