Results 121 to 130 of about 632,171 (267)

Linking Persistent Identifiers At The British Library

, 2017
Presentation given at the Crossref-THOR outreach meeting: Much more than infrastructure: working together to connect research.
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Persistent Identifiers: Towards the FAIRness of Archaeological Samples for Scientific Analysis

Internet Archaeology
This paper explores how persistent identifiers (PIDs) and standardised metadata profiles can foster the FAIR (Findable, Accessible, Interoperable, and Reusable) management of archaeological samples and their associated analytical data.
Yiu-Kang Hsu, Rorie Edmunds
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

How persistent identifiers can save scientists time. [PDF]

FEMS Microbiol Lett, 2018
Meadows A, Haak L.
europepmc   +1 more source

Persistent Identifiers distributed system for Cultural Heritage digital objects

, 2008
In this paper, we present a prototype with a novel resolution architecture for an URN based Persistent Identifiers (PI) system in Italy. We describe a distribute approach for implementing the NBN namespace system and illustrate the ...
Ernesto Damiani, Emanuele Bellini, Maurizio Lunghi, Cristiano Fugazza, Chiara Cirinnà   +4 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Persistent Identifiers: Fundamental building blocks for RI infrastructure

, 2018
"Persistent Identifiers: Fundamental building blocks for RI infrastructure" was presented at the ORCID Netherlands Roundtable Meeting in Utrecht, Netherlands on September 28, 2018 by Clifford Tatum (SURF)
Clifford Tatum (567312)
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

No persistent Identifiers (PIDs)? No data management!

This presentation, intended for "repo builders" group, explains the importance of persistent identifiers in repository ...
Černohlávková, Petra
core   +1 more source