Results 71 to 80 of about 11,052,815 (324)
The Horcrux Protocol: A Method for Decentralized Biometric-based Self-sovereign Identity
Most user authentication methods and identity proving systems rely on a centralized database. Such information storage presents a single point of compromise from a security perspective.
Callahan, John, Othman, Asem
core +1 more source
Maintaining consistency in distributed systems [PDF]
In systems designed as assemblies of independently developed components, concurrent access to data or data structures normally arises within individual programs, and is controlled using mutual exclusion constructs, such as semaphores and monitors.
Birman, Kenneth P.
core +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Reassessment of persistent symptoms, self-reported COVID-19 infection and SARS-CoV-2 serology in the SAPRIS-SERO cohort: identifying possible sub-syndromes of Long Covid [PDF]
Nicola Spiers
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Digital Scholarly Journals Are Poorly Preserved: A Study of 7 Million Articles
Introduction: Digital preservation underpins the persistence of scholarly links and citations through the digital object identifier (DOI) system. We do not currently know, at scale, the extent to which articles assigned a DOI are adequately preserved ...
Martin Paul Eve
doaj +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Persistent Identifiers for Instruments and Facilities: Current State, Challenges, and Opportunities
Objective: Persistent Identifiers (PIDs) are central to the vision of open science described in the FAIR Principles. However, the use of PIDs for scientific instruments and facilities is decentralized and fragmented.
Aditya Ranganath +6 more
doaj +2 more sources
Data stream management systems (DSMS) so far focus on event queries and hardly consider combined queries to both data from event streams and from a database.
Brodt, Simon, Bry, François
core +4 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

