Results 71 to 80 of about 632,171 (267)

Persistent Identifiers for Instruments and Facilities: Current State, Challenges, and Opportunities

Journal of eScience Librarianship
Objective: Persistent Identifiers (PIDs) are central to the vision of open science described in the FAIR Principles. However, the use of PIDs for scientific instruments and facilities is decentralized and fragmented.
Aditya Ranganath, Andrew Johnson, Claudius Mundoma, Greg Stosmeister, Matthew Mayernik, Matthew Murray, Renaine Julian   +6 more
doaj   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Index-Based Persistent Document Identifiers [PDF]

Information Retrieval, 2005
The infrastructure of a typical search engine can be used to calculate and resolve persistent document identifiers: a string that can uniquely identify and locate a document on the Internet without reference to its original location (URL). Bookmarking a document using such an identifier allows its retrieval even if the document's URL, and, in many ...
openaire   +1 more source

FDR-persistent identifiers sent together in same network connection (and so trivially linkable), plus whether Google Ad ID is sent in the same connection (so making it trivially linkable to the FDR-persistent identifiers).

, 2023
FDR-persistent identifiers sent together in same network connection (and so trivially linkable), plus whether Google Ad ID is sent in the same connection (so making it trivially linkable to the FDR-persistent identifiers).
Haoyu Liu (1918348), Douglas J. Leith (9443642), Paul Patras (14445239)   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Persistent Identifiers and URLs [PDF]

, 2015
Just like the rest of the internet, much of our scholarly infrastructure is built around the Hypertext Transfer Protocol (HTTP), increasingly HTTPS for security, and soon HTTP/2 for better performance. In this infrastructure Universal Resource Locators (URLs) are essential to locate resources (sic) such as scholarly articles, datasets, researchers ...
openaire   +1 more source

ePIC - Persistent Identifiers for eResearch

, 2015
Presented at: Persistent Identifiers: Enabling Services for Data Intensive Research DataCite and EPIC Monday, September 21, 2015 from 1:00 PM to 6:00 PM (CEST) Paris ...
Schwardmann, Ulrich, Schwardmann, Ulrich (5247406)   +1 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source