Results 71 to 80 of about 82,187 (270)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Compensation methods to support generic graph editing: A case study in automated verification of schema requirements for an advanced transaction model [PDF]
, 1999 Compensation plays an important role in advanced transaction models, cooperative work, and workflow systems. However, compensation operations are often simply written as a^−1 in transaction model literature. This notation ignores any operation parameters,
Even, S.J., Spelt, D.
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
DataCite - A global registration agency for research data [PDF]
Since 2005, the German National Library of Science and Technology (TIB) has offered a successful Digital Object Identifier (DOI) registration service for persistent identification of research data.
Jan Brase
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Implementing Persistent Identifiers
, 2019 Traditionally, organisations have relied on URL hyperlinks to provide interested parties with access to their digitised content via the internet. However, over time, more and more of these hyperlinks are ‘broken’. The URL relies on providing the specific location details for a document.
Hilse, Hans-Werner, Kothe, Jochen
openaire +1 more source
Index-Based Persistent Document Identifiers [PDF]
Information Retrieval, 2005 The infrastructure of a typical search engine can be used to calculate and resolve persistent document identifiers: a string that can uniquely identify and locate a document on the Internet without reference to its original location (URL). Bookmarking a document using such an identifier allows its retrieval even if the document's URL, and, in many ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Normalizing Resource Identifiers using Lexicons in the Global Change Information System: Linking Earth Science Identifiers, Concepts, and Communities [PDF]
Earth Science informatics involves collaboration between multiple groups of people with diverse specializations and goals,often using variations in terminology to refer to common resources.
Aulenbach, Steven +5 more
core +1 more source