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Persisters, Persistent Infections and the Yin–Yang Model
Emerging Microbes and Infections, 2014 Persisters are a small fraction of quiescent bacterial cells that survive lethal antibiotics or stresses but can regrow under appropriate conditions.
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Antibiotics, 2015 To identify effective compounds that are active against Staphylococcus aureus (S. aureus) persisters, we screened a clinical drug library consisting of 1524 compounds and identified six drug candidates that had anti-persister activity: tosufloxacin ...
Peng Cui, Jie Feng
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Bioactive Materials, 2022 Methicillin-resistant Staphylococcus aureus (MRSA), biofilms, and persisters are three major factors leading to recurrent and recalcitrant implant infections. Although antibiotics are still the primary treatment for chronic implant infections in clinical,
Minqi Wang, Haozheng Tang, Hongtao Yang
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Persisting Cancer Cells Are Different From Bacterial Persisters [PDF]
Trends in CancerThe persistence of drug-sensitive tumors poses a significant challenge in cancer treatment. The concept of bacterial persisters, which are a subpopulation of bacteria that survive lethal antibiotic doses, is frequently used to compare to residual disease
Sven Rottenberg, Morgane Decollogny
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ACM Transactions on Database Systems, 2022
A persistent data structure , also known as a multiversion data structure in the database literature, is a data structure that preserves all its previous versions as it is updated over time.
Tianjing Zeng +5 more
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A persistent data structure , also known as a multiversion data structure in the database literature, is a data structure that preserves all its previous versions as it is updated over time.
Tianjing Zeng +5 more
openaire +3 more sources
Nonlinearity, 2004
Summary: Ecological vector fields \(\dot x_j= x_if_i(x)\) on the nonnegative cone \(\mathbb{R}^n_+\) on \(\mathbb{R}^n\) are often used to describe the dynamics of \(n\) interacting species. These vector fields are called permanent (or uniformly persistent) if the boundary \(\partial\mathbb{R}^n_+\) of the nonnegative cone is repelling. We construct an
Hofbauer, Josef, Schreiber, Sebastian J.
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Summary: Ecological vector fields \(\dot x_j= x_if_i(x)\) on the nonnegative cone \(\mathbb{R}^n_+\) on \(\mathbb{R}^n\) are often used to describe the dynamics of \(n\) interacting species. These vector fields are called permanent (or uniformly persistent) if the boundary \(\partial\mathbb{R}^n_+\) of the nonnegative cone is repelling. We construct an
Hofbauer, Josef, Schreiber, Sebastian J.
openaire +1 more source
Frontiers in PharmacologyInfections associated with bacterial persisters are challenging to cure because they can evade antibiotics and regrow, often resulting in relapse.
Jae Seok Kim, Wonsik Lee, Eun Kyoung Seo
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Bacterial Persisters: Molecular Mechanisms and Therapeutic Development
Signal Transduction and Targeted TherapyPersisters refer to genetically drug susceptible quiescent (non-growing or slow growing) bacteria that survive in stress environments such as antibiotic exposure, acidic and starvation conditions.
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The Persistent Mystery of Adenovirus Persistence
Trends in Microbiology, 2016Human adenovirus (HAdV) often causes acute, lytic infections which are readily recapitulated in culture models. Alternatively, HAdV can establish persistent infections which have been difficult to reproduce in cell culture and are poorly understood. A recent study reveals how HAdV can re-task the host cell antiviral response to establish persistence.
Cason R, King, Ali, Zhang, Joe S, Mymryk
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