Results 81 to 90 of about 54,694 (209)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Career adaptability and work engagement: the roles of person–organization fit and job insecurity

open access: yesBMC Psychology
Purpose The purpose of this study is to examine the relationship between employees’ career adaptability and work engagement. Specifically, this study investigates the mediating role of person‒organization fit in the relationship between career ...
Qishan Chen   +5 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The Impact of Career Adaptability on Career Plateau: The Mediating Role of Person-Job Fit and Person-Organization Fit [PDF]

open access: yesفرایند مدیریت و توسعه, 2019
This research has been conducted to examine the impact of career adaptability on career plateau by explaining the mediating role of person-job fit and person-organization fit. In terms of purpose, the study is applied and it was conducted by descriptive /
Hojjat Taheri Goodarzi, Neda Norouzi
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Graph-based adaptive feature fusion neural network model for person-job fit

open access: yesComplex & Intelligent Systems
Online recruitment services are rapidly transforming traditional hiring practices in the job market. Accurate person-job fit is crucial for intelligent recruitment. Previous studies on person-job fit fail to explore job seekers’ resume information from a
Xia Xue   +7 more
doaj   +1 more source

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