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Personalized Medicine: A Personal View
Clinical Pharmacology & Therapeutics, 2012Personalized medicine is a strategy to prevent, diagnose, and treat disease so as to achieve an optimal result for the individual. The sequencing of the human genome and other technological advances have revealed the extent of genetic diversity and the relative contribution of genetic and nongenetic factors to human health, disease, and drug response ...
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Personalized precision medicine
Bio-Algorithms and Med-Systems, 2019Abstract Along with the development of modern science, medical knowledge and therapy become more and more precise and personal as a consequence. Genetics and immunology participate in the progress in particular. They open the way to molecular knowledge, allowing precise interpretation of pathology in individual cases followed by finding ...
Leszek Konieczny, Irena Roterman
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Genomics and personalized medicine
International Journal of Pharmaceutics, 2011The role of genomics in personalized medicine continues to undergo profound changes, in step with dramatic technological advances. Ability to sequence the entire human genome with relative ease raises expectations that we can use an individual's complete genomic blueprint to understand disease risk and predicting therapy outcomes, thereby, optimizing ...
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Pharmacometabonomics and personalized medicine
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2013Background Pharmacometabonomics is a new branch of science, first described in 2006 and defined as ‘the prediction of the effects of a drug on the basis of a mathematical model of pre-dose metabolite profiles’. Pharmacometabonomics has been used to predict drug metabolism, pharmacokinetics (PK), drug safety and ...
Everett, Jeremy +2 more
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Nanobiotechnology and Personalized Medicine
2011This chapter will start with a definition and scope of personalized medicine and describe how various nanobiotechnologies will contribute to its development. Nanodiagnostics and its combination with therapeutics as well as nanoparticle-based drug delivery will play an important role.
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Biobanking for Personalized Medicine
2015A biobank is an entity that collects, processes, stores, and distributes biospecimens and relevant data for use in basic, translational, and clinical research. Biobanking of high-quality human biospecimens such as tissue, blood and other bodily fluids along with associated patient clinical information provides a fundamental scientific infrastructure ...
Angen, Liu, Kai, Pollard
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[Proteomics and personalized medicine].
Recenti progressi in medicina, 2013With the disclosure of the human genome a new era for bio-medicine has arisen, characterized by the challenge to investigate pathogenic mechanisms, studying simultaneously metabolites, DNA, RNA, and proteins. As a result, the "omics" revolution boomed, giving birth to a new medicine named "omics-based medicine".
Rocchiccioli S. +3 more
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Personalized Medicine in the NICU
The American Journal of Bioethics, 2013Two of the criticisms of the SUPPORT trial are closely related: first that there was no “usual care” group, which should have been included to make the trial informative, and second that because be...
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Personalizing precision medicine
Journal of the American Society of Hypertension, 2015Personalized medicine used to mean the individual attention each patient received from a caring physician, who took the time to explain the health problem, potential remedies, and attendant risks, and then administered the best possible treatment. We learned personalized medicine by observing master teachers and by practicing what they taught. The term
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