Results 121 to 130 of about 2,557,779 (357)
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
Getting personal: exploring the usage of persona in order to optimize the involvement of a living lab panel [PDF]
, 2015 iMinds Living Labs started with living lab research in 2009. Living lab research involves gathering user feedback on innovations implemented in a real-life context (Eriksson et al., 2005).
Logghe, Sara
core +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
IEEE AccessAccessibility and inclusion are fundamental human rights, enacted to ensure that everyone has equal access to digital content. However, in practice, a large number of interactive systems remain inaccessible, which prevents users from accessing essential ...
Paula Alexandra Silva +1 more
doaj +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Crecimiento empresarial: personas y tecnología en la nueva economía
Revista Empresa y Humanismo, 2000 La brusca irrupción de Internet y de las nuevas tecnologías en la empresa, y la globalización de los mercados de capitales han planteado a las empresas un nuevo reto, hasta ahora, menos prioritario: la necesidad de encontrar nuevas vías para el ...
Jordi Canals
doaj
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source