Results 91 to 100 of about 14,354,690 (343)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Experiences of meaningful occupation among diverse populations – A qualitative meta-ethnography

Scandinavian Journal of Occupational Therapy
Background Few studies synthesising knowledge about meaningful occupation are available. Meta-ethnography allows the synthesising of a variety of empirical findings and translational knowledge may be developed.Aim Investigate how individuals from diverse
Christel Leufstadius, Lisbeth Nilsson, Pia Hovbrandt   +2 more
doaj   +1 more source

Perspective, géométrie et esthétique chez Lambert (II)

, 2010
International audienceAu cours de notre premier article, nous avons tenté de déterminer le lecteur implicite de Lambert dans son traité de perspective (1759 / 1774) ; nous avons précisé les rapports qu'il établit entre la perspective, la géométrie et l ...
Eckes, Christophe
core   +2 more sources

In perspective: Tom Nairn [PDF]

, 1999
The 1960s saw an upsurge of separatist nationalisms at the core of the capitalist system, with the movements in Catalonia, Eskudai, Occitania, Quebec, Scotland, Wallonia and Wales all making their first serious impact during that decade.
Davidson, Neil
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Lessons learned from the development of a national registry on dementia care and support based on linked national health and administrative data

Learning Health Systems
Introduction This paper provides insight into the development of the Dutch Dementia Care and Support Registry and the lessons that can be learned from it.
Iris van derHeide, Anneke L. Francke, Carola Döpp, Marianne Heins, Hein P. J. vanHout, Robert A. Verheij, Karlijn J. Joling   +6 more
doaj   +1 more source

Les formes sociales de l’homosexualité masculine à Bamako dans une perspective comparée : entre tactiques et mobilisations collectives [PDF]

, 2013
Christophe Broqua
openalex   +1 more source

Perspective Reasoning and the Solution to the Sleeping Beauty Problem [PDF]

, 2018
This paper proposes a new explanation for the paradoxes related to anthropic reasoning. Solutions to the Sleeping Beauty Problem and the Doomsday argument are discussed in detail.
Gao, Xianda
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Perspectives … [PDF]

Perspectives on Medical Education, 2012
None
openaire   +3 more sources