Results 91 to 100 of about 4,203,675 (344)
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Química NovaRelevant historical aspects concerning ideal gases were briefly reviewed to provide a condensed resource for the undergraduate student of chemistry. The importance of the barometer and the concept of atmospheric pressure were reviewed and discussed.
Leonardo M. Da Silva +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
The Symbolic Narrative of the Body in Murniasih’s Paintings : an Hermeneutical Study [PDF]
, 2009 This article is a study on I.G.K Murniasih’s paintings on the perspective of hermeneutics. It focuses on the aspects of symbolic-narrative, i.e. the narrative elements which optimized the potentials of symbols.
Acep , Iwan Saidi
core
Characterizing the Shape of Activation Space in Deep Neural Networks
, 2019 The representations learned by deep neural networks are difficult to interpret in part due to their large parameter space and the complexities introduced by their multi-layer structure.
Gebhart, Thomas +2 more
core +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Probabilistic Inference in Queueing Networks [PDF]
, 2008 Although queueing models have long been used to model the performance of computer systems, they are out of favor with practitioners, because they have a reputation for requiring unrealistic distributional assumptions.
Jordan, Michael I., Sutton, Charles
core +1 more source
Effects of Stereoscopic 3D Contents on the Process of Learning to Build a Handmade PC
Knowledge Management & E-Learning: An International Journal, 2011 We previously developed Web3D contents that simulate the procedure for assembling a handmade PC. The original motivation for this project was to enable media-informatics students to deepen their understanding of PC hardware.
Tosh Yamamoto +4 more
doaj
Insights into functional polymer-based organic-inorganic nanocomposites as leather finishes
Journal of Leather Science and Engineering, 2019 Nowadays, the increasing demands from consumer challenges the traditional leather products. Traditional polymer leather finishes gradually lose their dominant position in the market.
Qianqian Fan, Jianzhong Ma, Qunna Xu
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source