Results 71 to 80 of about 505,854 (305)

Think Spatially With Game Engine

open access: yesISPRS International Journal of Geo-Information, 2020
Spatial thinking and spatial orientation skills are involved in tasks related to the recognition of landforms, mapping, spatial interpretation, and landscape analysis, and can be developed with specific training.
Carlos Carbonell-Carrera   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Generalized load graphical forecasting method based on modal decomposition

open access: yesGlobal Energy Interconnection
In a “low-carbon” context, the power load is affected by the coupling of multiple factors, which gradually evolves from the traditional “pure load” to the generalized load with the dual characteristics of “load + power supply.” Traditional time-series ...
Lizhen Wu   +3 more
doaj   +1 more source

Insights into functional polymer-based organic-inorganic nanocomposites as leather finishes

open access: yesJournal of Leather Science and Engineering, 2019
Nowadays, the increasing demands from consumer challenges the traditional leather products. Traditional polymer leather finishes gradually lose their dominant position in the market.
Qianqian Fan, Jianzhong Ma, Qunna Xu
doaj   +1 more source

When is a Network a Network? Multi-Order Graphical Model Selection in Pathways and Temporal Networks

open access: yes, 2017
We introduce a framework for the modeling of sequential data capturing pathways of varying lengths observed in a network. Such data are important, e.g., when studying click streams in information networks, travel patterns in transportation systems ...
Costa Alceu Ferraz   +2 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Stakeholder Perspectives to Support Graphical User Interface Design for Children with Autism Spectrum Disorder: A Qualitative Study [PDF]

open access: gold, 2021
Betania Groba   +5 more
openalex   +1 more source

Graphical model-based approaches to target tracking in sensor networks: an overview of some recent work and challenges [PDF]

open access: yes, 2007
Sensor Networks have provided a technology base for distributed target tracking applications among others. Conventional centralized approaches to the problem lack scalability in such a scenario where a large number of sensors provide measurements ...
Cetin, Mujdat   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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