Results 81 to 90 of about 505,854 (305)

A Development Perspective of Point-Based Computer Graphics

open access: yesScience Insights, 2021
Every object has its characteristic shape, appearance and responses to physical interactions. Computer graphics center on those three components of an object to bring them onto the computer display. With the rapid development of three dimensional (3D) printing technology, the accuracy of the focused object’s geometry was put forward.
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Visualizing Three-Qubit Entanglement

open access: yesEntropy
We present a graphical framework to represent entanglement in three-qubit states. The geometry associated with each entanglement class and type is analyzed, revealing distinct structural features.
Alfred Benedito, Germán Sierra
doaj   +1 more source

Imperial strategy of cancer cells through mitochondrial transfer

open access: yesMolecular Oncology, EarlyView.
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley   +1 more source

An IMS LD Graphic Editor using the graphs representation for modifying the course structures

open access: yesJournal of Interactive Media in Education, 2005
Commentary on: Chapter 20: Delivery of Learning Design: the Explor@ System?s Case. (Paquette, Marino, De la Teja, Léonard, & Lundgren-Cayrol, 2005) Abstract: We developed a Web portal, named netUniversité, that enables the teachers to create their ...
Ecaterina Giacomini Pacurar   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Individual Resilience From a Religious Perspective: A Systemic Approach [PDF]

open access: yesHealth, Spirituality and Medical Ethics, 2023
Background and Objectives: Islam is a lifestyle consistent with world realities that guide humans through difficulties in life. Resilience has been highly recommended in religious doctrine, yet has been less explored within a comprehensive scientific ...
Pezhman Bagheri, Vajihe Armanmehr
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Get Beyond Limits: From Colloidal Tectonics Concept to the Engineering of Eco-Friendly Catalytic Systems

open access: yesFrontiers in Chemistry, 2018
The interactions between two or more molecules or colloidal particles can be used to obtain a variety of self-assembled systems called supramolecules or supracolloids. There is a clear, but neglected, convergence between these two fields.
Loïc Leclercq
doaj   +1 more source

Interactive orbital proximity operations planning system [PDF]

open access: yes
An interactive, graphical proximity operations planning system was developed which allows on-site design of efficient, complex, multiburn maneuvers in the dynamic multispacecraft environment about the space station. Maneuvering takes place in, as well as
Ellis, Stephen R., Grunwald, Arthur J.
core   +1 more source

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