Results 91 to 100 of about 3,579,984 (327)

Opening up the echo chamber: Perspective taking in social science education

open access: yesActa Didactica Norden, 2020
Public discourse is increasingly polarised when it comes to contemporary political and controversial issues. The debating climate has been described as an “echo chamber” where we tend to find arguments supporting our own established truths rather than ...
Johan Sandahl
doaj   +1 more source

Reducing Stigma toward the Transgender Community: An Evaluation of a Humanizing and Perspective-Taking Intervention [PDF]

open access: yes, 2012
Transgender (TG) individuals, or those whose gender identities, expressions and/or behaviors differ from their biological sex (Kirk & Kulkarni, 2006) feel there is a pervasive pattern of discrimination and prejudice directed toward them (Lombardi et al.,
Hillman, Kimberly, Ordoubadi, Fatemah
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The relation between spatial perspective taking and inhibitory control in 6-year-old children [PDF]

open access: yes, 2017
Developmental research on spatial perspective taking has shown that young children are able to solve perspective-taking problems under favorable circumstances, but they have difficulties succeeding in classic tasks involving a conflict between one’s ...
Baumeler, Denise, Frick, Andrea
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Sensory substitution: the spatial updating of auditory scenes ‘mimics’ the spatial updating of visual scenes

open access: yesFrontiers in Behavioral Neuroscience, 2016
Visual-to-auditory sensory substitution is used to convey visual information through audition, and it was initially created to compensate for blindness; it consists of software converting the visual images captured by a video-camera into the equivalent ...
Achille ePasqualotto, Tayfun eEsenkaya
doaj   +1 more source

Reducing Stigma toward the Transgender Community: An Evaluation of a Humanizing and Perspective-Taking Intervention [PDF]

open access: yes, 2014
Transgender (TG) individuals are an understudied group at high risk of experiencing discrimination and associated adverse mental health outcomes (IOM, 2011). Although many studies demonstrate that contact reduces negative attitudes toward out-groups, few
Hillman, Kimberly M.   +4 more
core   +1 more source

Liquid retail:cultural perspectives on marketplace transformation [PDF]

open access: yes, 2018
Inspired by Bauman’s notion of ‘liquidity’, we problematize the socio-cultural dynamics taking place in contemporary retail. The notion of liquid retail enables reserachers to untangle marketplace transformation and to highlight developments centred ...
Bajde, Domen   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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