Results 21 to 30 of about 636,928 (222)

Evaluation of Immunobiological Properties of Bordetella pertussis Vaccine Strains

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The study performed as part of evaluation of immunobiological properties of Bordetella pertussis vaccine strains offered an opportunity to standardize pertussis bacterial mass based on the content of surface antigens — agglutinogens 1, 2 and 3.
I. A. Alekseeva, O. V. Perelygina
doaj   +1 more source

The association between vaccine hesitancy and pertussis: a systematic review and meta-analysis

open access: yesItalian Journal of Pediatrics, 2023
Background Robust routine immunization schedules for pertussis-containing vaccines have been applied for years, but pertussis outbreaks remain a worldwide problem. This study aimed to investigate the association between vaccine hesitancy and pertussis in
Yuning Wang   +5 more
doaj   +1 more source

Expression of Bordetella pertussis Antigens Fused to Different Vectors and Their Effectiveness as Vaccines

open access: yesVaccines, 2021
Pertussis is an acute respiratory tract infection caused by Bordetella pertussis. Even though its current vaccine coverage is relatively broad, they still have some shortcomings such as short protection time and might be incapable of blocking the spread ...
Han Xu   +10 more
doaj   +1 more source

Rare Detection of Bordetella pertussis Pertactin-Deficient Strains in Argentina

open access: yesEmerging Infectious Diseases, 2019
Pertussis resurgence had been attributed to waning vaccine immunity and Bordetella pertussis adaptation to escape vaccine-induced immunity. Circulating bacteria differ genotypically from strains used in production of pertussis vaccine.
Francisco Carriquiriborde   +6 more
doaj   +1 more source

Immunogenicity of a Candidate DTacP-sIPV Combined Vaccine and Its Protection Efficacy against Pertussis in a Rhesus Macaque Model

open access: yesVaccines, 2021
The research and development of a pertussis-combined vaccine using a novel inactivated poliovirus vaccine made from the Sabin strain (sIPV) is of great significance in the polio eradication project and to address the recent resurge in pertussis.
Xiaoyu Wang   +7 more
doaj   +1 more source

Pertussis Vaccine [PDF]

open access: yesPediatric Infectious Disease Journal, 2009
A critical level of serum IgG pertussis toxin antibody is both essential and sufficient to confer individual and herd immunity to pertussis. Monocomponent pertussis toxoid conferred such immunity in Sweden and in Denmark. We refute the notion that filamentous hemagglutinin, pertactin, and fimbriae add to the immunity conferred by pertussis toxoid and ...
John B, Robbins   +5 more
openaire   +2 more sources

Acellular Pertussis Vaccine Effectiveness Over Time

open access: yesPediatrics, 2019
Compared with children fully DTaP vaccinated, unvaccinated and undervaccinated children were at a greater risk of pertussis. However, most pertussis cases occurred among age-appropriately vaccinated children.
O. Zerbo   +5 more
semanticscholar   +1 more source

Intranasal acellular pertussis vaccine provides mucosal immunity and protects mice from Bordetella pertussis

open access: yesnpj Vaccines, 2019
Current acellular pertussis vaccines fall short of optimal protection against the human respiratory pathogen Bordetella pertussis resulting in increased incidence of a previously controlled vaccine- preventable disease.
Dylan T. Boehm   +15 more
semanticscholar   +1 more source

Assessment of Pertussis Vaccine Protective Effectiveness in Children in the Amhara Regional State, Ethiopia

open access: yesInternational Journal of Microbiology, 2020
Background. Bordetella pertussis is a human pathogen which causes pertussis, or whooping cough. The diphtheria-tetanus-pertussis immunization has significantly reduced the morbidity and mortality of pertussis globally.
Solomon Taye   +3 more
doaj   +1 more source

A Randomized Controlled Trial of the Safety and Immunogenicity of Tetanus, Diphtheria, and Acellular Pertussis Vaccine Immunization During Pregnancy and Subsequent Infant Immune Response

open access: yesClinical Infectious Diseases, 2018
Background Immunization of pregnant women with tetanus-diphtheria-acellular pertussis vaccine (Tdap) provides protection against pertussis to the newborn infant.
Scott A. Halperin   +19 more
semanticscholar   +1 more source

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