Results 61 to 70 of about 636,928 (222)

Reemergence of Pertussis in the Highly Vaccinated Population of The Netherlands: Observations on Surveillance Data

Emerging Infectious Diseases, 2000
We analyzed pertussis reporting, death, hospitalization, and serodiagnostic data from 1976 to 1998 to help explain the cause of the 1996 pertussis outbreak in the Netherlands. The unexpected outbreak was detected by an increase in pertussis reporting and
Hester E. de Melker, J.F.P. Schellekens, S.E. Neppelenbroek, F.R. Mooi, H.C. Rümke, M.A.E. Conyn-van Spaendonck   +5 more
doaj   +1 more source

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine

Scientific Reports, 2016
The demand for improved pertussis vaccines is urgent due to the resurgence of whooping cough. A deeper understanding of the mode of action of pertussis vaccines is required to achieve this improvement.
R. Raeven, J. Brummelman, J. Pennings, L. van der Maas, W. Tilstra, K. Helm, E. van Riet, W. Jiskoot, C. V. van Els, W. Han, G. Kersten, B. Metz   +11 more
semanticscholar   +1 more source

Trust Norms, Distrust, and Worst‐Case Defiance in the COVID‐19 Pandemic

Regulation &Governance, EarlyView.
ABSTRACT When pandemics threaten, governments are expected to protect citizens. Trustworthiness and trust are central to meeting public expectations. Motivational posturing theory differentiates resistant and dismissive defiance during the COVID‐19 pandemic.
Valerie Braithwaite
wiley   +1 more source

Understanding the Epidemiology of Pertussis in Denmark

Acta Paediatrica, EarlyView.
Tine Dalby, Aoife Ronayne, Peter Henrik Andersen   +2 more
wiley   +1 more source

Content and Factors Influencing Health Education in Immunisation Clinics in Nigeria

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Most parents in Nigeria receive childhood vaccine education in a group clinic setting. These health talks are not standardised, and little is known about the topics addressed, how these topics are chosen, and how parents experience these talks. This study aimed to fill this knowledge gap.
Osayame A. Ekhaguere, Nnette Ekpenyong, Esosa F. Mohammed, Fatima Lawan Bukar, Angela Oyo‐Ita, Jessica Kaufman   +5 more
wiley   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Protective Activity and Safety of Acellular Pertussis Vaccine from Vaccine and Freshly Isolated Strain Bordetella pertussis

Эпидемиология и вакцинопрофилактика, 2017
Goal. Study of the protective activity and safety of acellular pertussis vaccine (APV) using freshly isolated strain of B. pertussis. Materials and methods. Mice-hybrids F1 (CBAxC57Bl6). The B. pertussis strains: vaccine strains No. 305, No. 203, freshly
E. M. Zaitsev, I. G. Bazhanova, M. V. Britsina   +2 more
doaj   +1 more source

A Phase I Clinical Study of a Live Attenuated Bordetella pertussis Vaccine - BPZE1; A Single Centre, Double-Blind, Placebo-Controlled, Dose-Escalating Study of BPZE1 Given Intranasally to Healthy Adult Male Volunteers

PLoS ONE, 2014
Background Acellular pertussis vaccines do not control pertussis. A new approach to offer protection to infants is necessary. BPZE1, a genetically modified Bordetella pertussis strain, was developed as a live attenuated nasal pertussis vaccine by ...
R. Thorstensson, B. Trollfors, N. Al-Tawil, Maja Jahnmatz, Jakob Bergström, M. Ljungman, A. Törner, L. Wehlin, Annie Van Broekhoven, F. Bosman, A. Debrie, N. Mielcarek, C. Locht   +12 more
semanticscholar   +1 more source

Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors

International Journal of Dermatology, Volume 65, Issue 2, Page 230-237, February 2026.
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín, Carolina Moreno, Ricardo Ruiz‐Villaverde, Esther Serra‐Baldrich, Irene Hernández‐Martín, Maria del Pilar Fortes   +5 more
wiley   +1 more source

Pertactin deficiency of Bordetella pertussis: Insights into epidemiology, and perspectives on surveillance and public health impact

Human Vaccines & Immunotherapeutics
Pertussis resurgence has been documented even in countries with high pediatric vaccine coverage. The proportion of Bordetella pertussis isolates not expressing pertactin (PRN) has increased in several countries where acellular pertussis (aP) vaccines are
Ulrich Heininger, Helena Martini, Jennifer Eeuwijk, Ivana Prokić, Adrienne P. Guignard, Elisa Turriani, Maurine Duchenne, Valérie Berlaimont   +7 more
doaj   +1 more source