Results 61 to 70 of about 706 (159)

Fagopyrins from Buckwheat Flowers: Structural and Stereochemical Characterization Through Combined NMR/CD Spectroscopy and Theoretical Calculations

Chemistry – A European Journal, Volume 30, Issue 33, June 12, 2024.
For the first time, nine fagopyrin isomers have been structurally characterized and their stereochemistry fully elucidated by integrated 1H‐NMR and CD spectroscopy studies. The presence of two different heterocyclic ring substituents, two stereogenic centers and the inherent axial chirality of the aromatic system provides a complex stereochemical ...
Valerio Galbusera, Benedetta Lattuada, Andrea Pinto, Alberto Barbiroli, Gigliola Borgonovo, Enzio M. Ragg   +5 more
wiley   +1 more source

Synthesis of the Altertoxin I Framework

European Journal of Organic Chemistry, Volume 27, Issue 3, January 15, 2024.
The core of the perylenequinone‐derived mycotoxin altertoxin I was synthesized either from 3‐hydroxyacetophenone or from 1,5‐dihydroxynaphthalene, where Suzuki couplings, Ullmann couplings, McMurry olefinations, and Friedel‐Crafts acetylation were key steps in the respective syntheses.
Maximilian Gutsche, Dominik Pfaff, Joachim Podlech   +2 more
wiley   +1 more source

Design, Synthesis, and Investigation of Protein Kinase C Inhibitors: Total Syntheses of (+)-Calphostin D, (+)- Phleichrome, Cercosporin and New Photoactive Perylenequinones

Journal of the American Chemical Society, 2009
The total syntheses of the PKC inhibitors (+)-calphostin D, (+)-phleichrome, cercosporin, and 10 novel perylenequinones are detailed. The highly convergent and flexible strategy developed employed an enantioselective oxidative biaryl coupling and a ...
Barbara J. Morgan, S. Dey, S. Johnson, M. Kozlowski   +3 more
semanticscholar   +1 more source

Synthesis of Octahydroperylene, the Framework of Altertoxin III

European Journal of Organic Chemistry, Volume 27, Issue 3, January 15, 2024.
The cis‐configured octahydroperylene core, present in perylenequinone‐derived mycotoxins like altertoxin III was synthesized from anthraflavic acid in four steps. Abstract Routes to the framework of perylenequinone‐derived mycotoxins of the dihydroanthracene type are described. Starting with anthracene derivatives, attachment of C3 units at positions 9
Maximilian Gutsche, Joachim Podlech
wiley   +1 more source

Perylenequinone Natural Products: Enantioselective Synthesis of the Oxidized Pentacyclic Core [PDF]

The Journal of Organic Chemistry, 2009
An enantioselective approach to the perylenequinone core found in the mold perylenequinone natural products is outlined. Specifically, the first asymmetric syntheses of helical chiral perylenequinones absent any additional stereogenic centers are described.
Carol A, Mulrooney, Barbara J, Morgan, Xiaolin, Li, Marisa C, Kozlowski   +3 more
openaire   +2 more sources

Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem cell line.

World Journal of Gastroenterology, 2003
AIM To investigate the photodynamic inhibitory effects of Elsinochrome A (EA), Hypocrellin A (HA) and Hypocrellin B (HB) on human colorectal carcinoma Hce-8693 cells and rhesus monkey embryonic stem R366.4 cells, via inducing apoptosis.
Lan Ma, Hong Tai, Cong Li, Yu Zhang, Zehua Wang, W. Ji   +5 more
semanticscholar   +1 more source

Alternatone A, an Unusual Perylenequinone-Related Compound from a Soft-Coral-Derived Strain of the Fungus Alternaria alternata

, 2019
A novel perylenequinone-related compound, alternatone A (1), with an unprecedented tricyclo­[6.3.1.02,7] dodecane skeleton, together with three known perylenequinones, altertoxin I (2), stemphyperylenol (3), and alterperylenol (4), was isolated from the ...
Chang-Yun Wang (542934), Kai-Ling Wang (842385), Chang-Lun Shao (842387), Dong-Lin Zhao (1523338), Lu-Jia Yang (4181341), Ting Shi (3955), Fei Cao (650073), Chao-Yi Wang (3491213)   +7 more
core   +2 more sources

Synthetic studies and biological evaluation of the perylenequinones: Total synthesis of cercosporin, (+)-calphostin D, (+)-phleichrome and novel photodynamic perylenequinones

, 2009
The efforts described in this dissertation encompass the total synthesis and biological assessment of the perylenequinone family of natural products.
Morgan, Barbara Jane
core  

Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis

, 2010
Perylenequinones that generate reactive oxygen species (ROS) when illuminated with visible light have been recommended as photodynamic chemotherapeutic agents.
Marconi M., Armato U., Whitfield J. F., Pacchiana R., Dal Pra I., Chiarini A.   +5 more
core   +1 more source

Alternaria alternata Isolated from Infected Pears (Pyrus communis) in Italy Produces Non-Host Toxins and Hydrolytic Enzymes as Infection Mechanisms and Exhibits Competitive Exclusion against Botrytis cinerea in Co-Infected Host Fruits. [PDF]

J Fungi (Basel), 2023
Castaldi S, Zorrilla JG, Petrillo C, Russo MT, Ambrosino P, Masi M, Cimmino A, Isticato R.   +7 more
europepmc   +1 more source