Results 41 to 50 of about 706 (159)

Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures

Photochemistry and Photobiology, Volume 96, Issue 3, Page 699-707, May/June 2020., 2020
The effects of cercosporin PDT on T47D breast adenocarcinoma as well as T98G and U87 human glioblastoma multiforme 3D cell cultures (spheroids). Abstract In the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of
Mantas Grigalavicius, Maria Mastrangelopoulou, Delmon Arous, Asta Juzeniene, Mathilde Ménard, Ellen Skarpen, Kristian Berg, Theodossis A. Theodossiou   +7 more
wiley   +1 more source

The AVR4 effector is involved in cercosporin biosynthesis and likely affects the virulence of Cercospora cf. flagellaris on soybean

Molecular Plant Pathology, Volume 21, Issue 1, Page 53-65, January 2020., 2020
Summary One of the most devastating fungal diseases of soybean in the southern USA is Cercospora leaf blight (CLB), which is caused mainly by Cercospora cf. flagellaris. Recent studies found that the fungal effector AVR4, originally identified in Cladosporium fulvum as a chitin‐binding protein, is highly conserved among other Cercospora species.
Josielle Santos Rezende, Marija Zivanovic, Maria Izabel Costa de Novaes, Zhi‐Yuan Chen   +3 more
wiley   +1 more source

Inhibitors of BRD4 Protein from a Marine-Derived Fungus Alternaria sp. NH-F6

Marine Drugs, 2017
Bromodomains (BRD) are readers of the epigenetic code that regulate gene transcription through their recognition of acetyl-lysine modified histone tails.
Hui Ding, Dashan Zhang, Biao Zhou, Zhongjun Ma   +3 more
doaj   +1 more source

Perylenequinone Natural Products: Enantioselective Synthesis of the Oxidized Pentacyclic Core

, 2016
An enantioselective approach to the perylenequinone core found in the mold perylenequinone natural products is outlined. Specifically, the first asymmetric syntheses of helical chiral perylenequinones absent any additional stereogenic centers are ...
Barbara J. Morgan (2328628), Carol A. Mulrooney (1957894), Xiaolin Li (397893), Marisa C. Kozlowski (1314135)   +3 more
core   +3 more sources

Design, Synthesis, and Investigation of Protein Kinase C Inhibitors: Total Syntheses of (+)-Calphostin D, (+)-Phleichrome, Cercosporin, and New Photoactive Perylenequinones

, 2016
The total syntheses of the PKC inhibitors (+)-calphostin D, (+)-phleichrome, cercosporin, and 10 novel perylenequinones are detailed. The highly convergent and flexible strategy developed employed an enantioselective oxidative biaryl coupling and a ...
Barbara J. Morgan (2328628), Sangeeta Dey (2364685), Marisa C. Kozlowski (1314135), Steven W. Johnson (2364682)   +3 more
core   +2 more sources

Antimicrobial and Antitumor Photodynamic Effects of Phleichrome from the Phytopathogenic Fungus Cladosporium Phlei

Mycobiology, 2018
Fungal perylenequinones have photodynamic activity and are promising photosensitizers for photodynamic therapy (PDT). Here, we investigated the bactericidal and antitumor activities of phleichrome from the fungal perylenequinone family in vitro ...
Kum-Kang So, Jeesun Chun, Dae-Hyuk Kim
doaj   +1 more source

Inducing perylenequinone production from a bambusicolous fungus Shiraia sp. S9 through co-culture with a fruiting body-associated bacterium Pseudomonas fulva SB1

Microbial Cell Factories, 2019
Background Fungal perylenequinonoid (PQ) pigments from Shiraia fruiting body have been well known as excellent photosensitizers for medical and agricultural uses. The fruiting bodies are colonized by a diverse bacterial community of unknown function.
Yan Jun Ma, Li Ping Zheng, Jian Wen Wang
doaj   +1 more source

Perylenequinone Natural Products: Evolution of the Total Synthesis of Cercosporin [PDF]

The Journal of Organic Chemistry, 2009
The evolution of the first total synthesis of perylenequinone cercosporin is described. The key features developed during these efforts include a biscuprate epoxide alkylation, installation of the methylidene acetal, palladium-catalyzed O-arylation, and C3,C3'-decarbonylation.
Barbara J, Morgan, Carol A, Mulrooney, Marisa C, Kozlowski   +2 more
openaire   +2 more sources

Effects of 5-Azacytidine on Growth and Hypocrellin Production of Shiraia bambusicola

Frontiers in Microbiology, 2018
Hypocrellins, fungal perylenequinones of Shiraia bambusicola are developed as important photodynamic therapy agents against cancers and viruses. Due to the limitation of the wild resources, the mycelium culture is a promising alternative for hypocrellin ...
Yan Jun Ma, Can Song Lu, Jian Wen Wang
doaj   +1 more source

The Rise of Stemphylium vesicarium: A Growing Threat to Pear Production in Europe

Plant Pathology, Volume 75, Issue 4, July‐August 2026.
Brown spot of pear, caused by the fungus Stemphylium vesicarium, was reported in Italy in 1975 and only recently, due to climate change and pesticide restrictions, it became a major threat for European pear production. New knowledge on this pathogen can allow the advent of new and effective control strategies.
Xueqin Chen, Milan Karas, Luca Dondini, Riccardo Baroncelli, Marina Collina, Elena Baraldi   +5 more
wiley   +1 more source