Results 101 to 110 of about 449,349 (233)

Automatic Synthesis and Micro PET/CT Imaging Study of 11C-DASB as a Serotonin Imaging Agent

Journal of Isotopes, 2015
Objectives: Automatic synthesis of 11C-DASB as a serotonin imaging agent was established and Micro PET/CT imaging with Wistar rat was performed. Methods: Optimization of 11C-DASB synthesis was established by modifying different 11C-methylation agents ...
ZHANG Xiao-jun, LI Yun-gang, ZHANG Jin-ming   +2 more
doaj   +1 more source

Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography [PDF]

, 2012
Preliminary investigation of the radioiodinated (S,S)-reboxetine analogue, 123I-INER, in baboons showed this tracer to have promise for imaging the noradrenaline transporter (NAT) using single photon emission computed tomography (SPECT).
Baldwin, Baldwin, Chang, Ding, Gandelman, Grandoso, Jobson, Jobson, Jobson, Kanegawa, Kiyono, Kung, Lakshmi, McConathy, Schou, Schou, Schou, Seibyl, Seneca, Smith, Stoddart, Tamagnan, Tavares, Tavares, Tejani-Butt, Zeng, Zoghbi   +26 more
core   +1 more source

Focal Spot, Winter 2006/2007 [PDF]

, 2007
https://digitalcommons.wustl.edu/focal_spot_archives/1104/thumbnail ...

core   +1 more source

First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma. [PDF]

, 2020
PurposeGDC-0084 is an oral, brain-penetrant small-molecule inhibitor of PI3K and mTOR. A first-in-human, phase I study was conducted in patients with recurrent high-grade glioma.Patients and methodsGDC-0084 was administered orally, once daily, to ...
Cloughesy, Timothy F, Coimbra, Alexandre F, Ellingson, Benjamin M, Gerstner, Elizabeth, Lee, Eudocia Q, Lu, Xuyang, Morrissey, Kari M, Mueller, Lars U, Olivero, Alan G, Rodon, Jordi, Wen, Patrick Y, Wilson, Timothy R   +11 more
core  

Multimodality Imaging of Integrin αvβ3 Expression

Theranostics, 2011
Over the last decade, integrin αvβ3 has been studied with every single molecular imaging modality. Since no single modality is perfect and sufficient to obtain all the necessary information for a particular question, combination of certain ...
Yin Zhang, Yunan Yang, Weibo Cai
doaj  

Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Novel PET/SPECT Imaging Probes for Diagnosis of Alzheimer’s Disease

Journal of Pharmacological Sciences, 2012
Alzheimer’s disease (AD) is a neurodegenerative disease of the brain associated with irreversible cognitive decline, memory impairment, and behavioral changes.
Masahiro Ono, Hideo Saji
doaj   +1 more source

Peptide PET Imaging: A Review of Recent Developments and a Look at the Future of Radiometal-Labeled Peptides in Medicine

Chemical & Biomedical Imaging
The development of peptide-based, radiometal-labeled PET imaging agents has seen an increase in attention due to the favorable properties the peptide backbone exhibits.
Majed Shabsigh, Lee A. Solomon
semanticscholar   +1 more source

Coordination Chemistry of Sulfur-Containing Bifunctional Chelators: Toward in Vivo Stabilization of ⁶⁴Cu PET Imaging Agents for Alzheimer's Disease. [PDF]

Inorg Chem, 2023
Yu Z, Blade G, Bouley BS, Dobrucki IT, Dobrucki LW, Mirica LM.   +5 more
europepmc   +1 more source

Small Molecule Optoacoustic Contrast Agents: An Unexplored Avenue for Enhancing In Vivo Imaging

Molecules, 2018
Almost every variety of medical imaging technique relies heavily on exogenous contrast agents to generate high-resolution images of biological structures.
Matt D. Laramie, Mary K. Smith, Fahad Marmarchi, Lacey R. McNally, Maged Henary   +4 more
doaj   +1 more source

Novel brain PET imaging agents: Strategies for imaging neuroinflammation in Alzheimer's disease and mild cognitive impairment. [PDF]

Front Immunol, 2022
Huang J.
europepmc   +1 more source