Automatic Synthesis and Micro PET/CT Imaging Study of 11C-DASB as a Serotonin Imaging Agent
Objectives: Automatic synthesis of 11C-DASB as a serotonin imaging agent was established and Micro PET/CT imaging with Wistar rat was performed. Methods: Optimization of 11C-DASB synthesis was established by modifying different 11C-methylation agents ...
ZHANG Xiao-jun +2 more
doaj +1 more source
Nanomedicine holds promise for the delivery of therapeutic and imaging agents to improve cancer treatment outcomes. Preclinical studies have demonstrated that high-density lipoprotein (HDL) nanoparticles accumulate in tumor tissue on intravenous ...
Vugts, Danielle J. +13 more
core +1 more source
The poly (adenosine-diphosphate (ADP) ribose) polymerase (PARP) family of enzymes has been of interest to researchers and clinicians for over fifty years, especially the first member of the family, PARP1.
Carney, Brandon
core
Coordination Chemistry of Sulfur-Containing Bifunctional Chelators: Toward in Vivo Stabilization of 64Cu PET Imaging Agents for Alzheimer's Disease. [PDF]
Yu Z +5 more
europepmc +1 more source
Hydrazine Derivatives as a Platform for Site-Specific Labelling of Peptides for in vivo Molecular Imaging of Disease [PDF]
The 6-hydrazinonicotinyl group, known as HYNIC, is an attractive bifunctional coupling agent for preparing 99mTc-labeled peptides and proteins for medical imaging.
Holland, Charlotte
core
18F‑Labeled BODIPY Dye: A Potential Prosthetic Group for Brain Hybrid PET/Optical Imaging Agents
There are few hybrid positron emission tomography (PET)/fluorescence imaging agents available for brain imaging. For this purpose, BODIPY dye is very attractive because one of its fluorine atoms can be readily exchanged with 18F, and it can be modified ...
Joon Young Choi (511908) +7 more
core +1 more source
Alzheimer’s disease (AD) is a neurodegenerative disease of the brain associated with irreversible cognitive decline, memory impairment, and behavioral changes.
Masahiro Ono, Hideo Saji
doaj +1 more source
Novel brain PET imaging agents: Strategies for imaging neuroinflammation in Alzheimer's disease and mild cognitive impairment. [PDF]
Huang J.
europepmc +1 more source
A generator-produced gallium-68 radiopharmaceutical for PET imaging of myocardial perfusion.
Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the parent isotope required for manufacturing 99Mo/99mTc generators, intensifies ...
Vijay Sharma +6 more
doaj +1 more source
Reducing the Kidney Uptake of High Contrast CXCR4 PET Imaging Agents via Linker Modifications. [PDF]
Kwon D +5 more
europepmc +1 more source

