Results 71 to 80 of about 110,621 (200)

Status and Prospect of Radiolabeled Small Molecule Inhibitors as Tumor Imaging Agents Targeting FAP

open access: yesJournal of Isotopes
: Fibroblast activation protein (FAP) exists in tumor stromal fibroblasts and is a significant target for tumor diagnosis and treatment recently. Among the radioactive FAP-targeted tumor imaging agents, small-molecule tracers have received the most ...
HAN Peiwen1, RUAN Qing1, 2, ZHANG Junbo1
doaj   +1 more source

Imaging in neuro-oncology

open access: yesTherapeutic Advances in Neurological Disorders, 2018
Imaging plays several key roles in managing brain tumors, including diagnosis, prognosis, and treatment response assessment. Ongoing challenges remain as new therapies emerge and there are urgent needs to find accurate and clinically feasible methods to ...
Hari Nandu   +2 more
doaj   +1 more source

Radiolabeling of Nucleic Acid Aptamers for Highly Sensitive Disease-Specific Molecular Imaging

open access: yesPharmaceuticals, 2018
Aptamers are short single-stranded DNA or RNA oligonucleotide ligand molecules with a unique three-dimensional shape, capable of binding to a defined molecular target with high affinity and specificity. Since their discovery, aptamers have been developed
Leila Hassanzadeh   +2 more
doaj   +1 more source

Studies on 68Ga-Based Agents for PET Imaging of Cancer and Inflammation [PDF]

open access: yes, 2011
Studies on 68Ga-Based Agents for PET Imaging of Cancer and Inflammation Positron emission tomography (PET) is based on the use of radiolabeled agents and facilitates in vivo imaging of biological processes, such as cancer.
Ujula, Tiina
core  

Research Progress of PET Molecular Probes Targeting Dopamine D3 Receptor

open access: yesJournal of Isotopes, 2023
Dopamine D3 receptors are closely related to drug addiction, Parkinson’s disease (PD), schizophrenia and other neuropsychiatric diseases. PET imaging agents that target dopamine D3 receptors can noninvasively show changes in receptor density and status ...
ZHANG Ge, XUE Jingquan, ZHAO Shilun, LIU Yu, YANG Wenjiang
doaj  

Development of Superparamagnetic Nanoparticles Coated with Polyacrylic Acid and Aluminum Hydroxide as an Efficient Contrast Agent for Multimodal Imaging

open access: yesNanomaterials, 2019
Early diagnosis of disease and follow-up of therapy is of vital importance for appropriate patient management since it allows rapid treatment, thereby reducing mortality and improving health and quality of life with lower expenditure for health care ...
Manuel Antonio González-Gómez   +9 more
doaj   +1 more source

Cardiovascular molecular imaging [PDF]

open access: yes, 2013
Although there have been significant improvements in the treatment of cardiovascular diseases they still remain the main cause of morbidity and mortality globally. Currently available diagnostic approaches may not be adequate to detect pathologic changes
Khanicheh, Elham
core   +1 more source

Neutral Metal-Chelating Compounds with High 64Cu Affinity for PET Imaging Applications in Alzheimer’s Disease

open access: yes, 2021
Positron emission tomography (PET), which uses positron-emitting radionuclides to visualize and measure processes in the human body, is a useful noninvasive diagnostic tool for Alzheimer’s disease (AD).
Truc T., Huynh   +6 more
core   +1 more source

Multimodality Imaging of Integrin αvβ3 Expression

open access: yesTheranostics, 2011
Over the last decade, integrin αvβ3 has been studied with every single molecular imaging modality. Since no single modality is perfect and sufficient to obtain all the necessary information for a particular question, combination of certain ...
Yin Zhang, Yunan Yang, Weibo Cai
doaj  

Targeted PET/MRI Imaging Super Probes: A Critical Review of Opportunities and Challenges

open access: yesInternational Journal of Nanomedicine, 2022
Anna Kastelik-Hryniewiecka,1,2 Pawel Jewula,3 Karolina Bakalorz,1 Gabriela Kramer-Marek,2,4 Nikodem Kuźnik1 1Silesian University of Technology, Faculty of Chemistry, Gliwice, Poland; 2Radiopharmacy and Preclinical PET Imaging Unit, Maria ...
Kastelik-Hryniewiecka A   +4 more
doaj  

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