Results 51 to 60 of about 110,621 (200)
CHIMIA, 2006 Imaging technologies have experienced rapid progress and are currently used widely both in medical diagnostics and in research. Imaging beyond X-ray and standard MRI became established in recent years.
Gerd Folkers +6 more
doaj +1 more source
Sigma receptor ligands: novel applications in cancer imaging and treatment [PDF]
, 2012 Sigma receptoren (subtypes sigma-1 en sigma-2) zijn unieke bindingsplaatsen die een aanzienlijk hogere expressie vertonen in kanker dan in gezond weefsel.
Rybczynska, Anna A., +1 more
core
Imaging ligands targeting glypican-3 receptor expression in hepatocellular carcinoma
, 2022 Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality. Early detection of HCC is important since potentially curative therapies exist in the initial stages of HCC; no curative therapies exist for late-stage HCC.
Zheng, David X. +2 more
core +1 more source
Bio-Protocol, 2019 Nuclear blood pool imaging using radiolabeled red blood cells has been used in the clinical setting for the evaluation of a number of medical conditions including gastrointestinal hemorrhage, impaired cardiac contractility, and altered cerebrovascular ...
Shaowei Wang, Jung Choi
doaj +1 more source
Synthesis and evaluation of indolinyl- and indolylphenylacetylenes as PET imaging agents for β-amyloid plaques [PDF]
Bioorganic & Medicinal Chemistry Letters, 2008 Two new phenylacetylene derivatives, 5-((4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)phenyl)ethynyl)indoline 8 and 5-((4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)phenyl)ethynyl)-1H-indole 14, targeting beta-amyloid (Abeta) plaques have been prepared. In vitro binding carried out in tissue homogenates prepared from postmortem AD brains with [(125)I]IMPY (6-iodo-2-(
Wenchao, Qu +9 more
openaire +2 more sources
A pilot study of PSMA-targeted F-18-DCFPyL PET imaging of patients with adenoid cystic carcinoma
Scientific ReportsAdenoid cystic carcinoma (ACC) is a rare malignancy of the salivary glands with poor long-term outcomes and with a need for improved imaging and therapeutic options.
Andrew F. Voter +10 more
doaj +1 more source
Imaging Alzheimer's disease pathophysiology with PET
Dementia & NeuropsychologiaAlzheimer's disease (AD) has been reconceptualised as a dynamic pathophysiological process characterized by preclinical, mild cognitive impairment (MCI), and dementia stages.
Lucas Porcello Schilling +9 more
doaj +1 more source
, 2004 Radiology is the fastest developing field of medicine and these unprecedented advances have been mainly due to improving computer technology. Digital imaging is a technology whereby images are acquired in a computer format, so that they can be easily ...
Vassallo, Pierre
core
PET of signal transduction pathways in cancer [PDF]
, 2012 Free to read\ud \ud In this era of systems biology, the tide of information derived from “omic” technologies (genomics, proteomics, etc.) has sparked a revolution in drug design, with many industrial and academic programs now embracing the concepts of ...
Holland, Jason P. +5 more
core +1 more source
Radiometal-Based PET/MRI Contrast Agents for Sensing Tumor Extracellular pH
Biosensors, 2022 Acidosis is a useful biomarker for tumor diagnoses and for evaluating early response to anti-cancer treatments. Despite these useful applications, there are few methods for non-invasively measuring tumor extracellular pH, and none are routinely used in ...
Alyssa C. Pollard +6 more
doaj +1 more source