Results 31 to 40 of about 76,229 (261)

A PET imaging agent for evaluating PARP-1 expression in ovarian cancer [PDF]

Journal of Clinical Investigation, 2018
Poly(ADP-ribose) polymerase (PARP) inhibitors are effective in a broad population of patients with ovarian cancer; however, resistance caused by low enzyme expression of the drug target PARP-1 remains to be clinically evaluated in this context. We hypothesize that PARP-1 expression is variable in ovarian cancer and can be quantified in primary and ...
Mehran Makvandi, Austin Pantel, Lauren Schwartz, Erin Schubert, Kuiying Xu, Chia-Ju Hsieh, Catherine Hou, Hyoung Kim, Chi-Chang Weng, Harrison Winters, Robert Doot, Michael D. Farwell, Daniel A. Pryma, Roger A. Greenberg, David A. Mankoff, Fiona Simpkins, Robert H. Mach, Lilie L. Lin   +17 more
openaire   +2 more sources

Review article liver metastases

Journal of the Belgian Society of Radiology, 2011
Liver metastases are a very common site of distant metastases. Detection and accurate characterization of liver metastases is of importance to guide therapy.
W Schima, C Koelblinger, G Lesnik, A Ba-Ssalamah   +3 more
doaj   +1 more source

Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer [PDF]

Theranostics, 2011
Les photosensibilisateurs à base de porphyrine sont des agents utiles pour la thérapie photodynamique (PDT) et l'imagerie par fluorescence du cancer. Les porphyrines sont également d'excellents chélateurs de métaux formant des métallocomplexes très stables, ce qui en fait des véhicules de livraison efficaces pour les radio-isotopes.
Jiyun Shi, Tracy Liu, Juan Chen, David Green, D. Jaffray, Brian C. Wilson, Fan Wang, Gang Zheng   +7 more
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer [PDF]

Cancer Prevention Research, 2011
Abstract COX-2 is a major contributor to the inflammatory response and cancer progression so it is an important target for prevention and therapy. COX-2 is absent or expressed at low levels in most epithelial cells but is found at high levels in inflammatory lesions, and many premalignant and malignant tumors.
Md Jashim, Uddin, Brenda C, Crews, Kebreab, Ghebreselasie, Imran, Huda, Philip J, Kingsley, Mohammad Sib, Ansari, Mohammed N, Tantawy, Jeffery, Reese, Lawrence J, Marnett   +8 more
openaire   +2 more sources

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Imaging in Biomedical Research: Mini-Symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 18, 2006

CHIMIA, 2006
Imaging technologies have experienced rapid progress and are currently used widely both in medical diagnostics and in research. Imaging beyond X-ray and standard MRI became established in recent years.
Gerd Folkers, Alumit Ishai, Markus Rudin, Pius August Schubiger, Matthias Bräutigam, Hanns Möhler, Hans Peter Märki   +6 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

From incidental positron emission uptake to in-vivo phenotyping: a short history of positron emission tomography in the study of atherosclerosis and the vulnerable plaque

Frontiers in Cardiovascular Medicine
Positron emission tomography (PET) imaging has evolved over the last 20 years to a powerful tool for assessing vascular biology. The incidental uptake of PET tracers to the vessel wall provided the substrate for creating dedicated protocols and ...
Retesh Bajaj, Retesh Bajaj, Ming Young Simon Wan, Kris Thielemans, Eren Ozan Bakır, Eren Ozan Bakır, Soe Maung, Soe Maung, Akash Sivananthan, Akash Sivananthan, Tom Crake, Tom Crake, Anthony Mathur, Anthony Mathur, Ryo Torii, Andreas Baumbach, Andreas Baumbach, Ashley Groves, Christos V. Bourantas, Christos V. Bourantas   +19 more
doaj   +1 more source