Results 31 to 40 of about 110,621 (200)

Synthesis and fluorine-18 radiolabeling of a phospholipid as a PET imaging agent for prostate cancer [PDF]

Nuclear Medicine and Biology, 2021
Altered lipid metabolism and subsequent changes in cellular lipid composition have been observed in prostate cancer cells, are associated with poor clinical outcome, and are promising targets for metabolic therapies. This study reports for the first time on the synthesis of a phospholipid radiotracer based on the phospholipid 1,2-didocosahexaenoyl-sn ...
Kwan, Kim H., Burvenich, Ingrid J.G., Centenera, Margaret M., Goh, Yit Wooi, Rigopoulos, Angela, Dehairs, Jonas, Swinnen, Johannes, Raj, Ganesh, Hoy, Andrew J., Butler, Lisa M., Scott, Andrew M., White, Jonathan M., Ackermann, Uwe   +12 more
openaire   +3 more sources

PET Radioligands for in Vivo Visualization of Neuroinflammation. [PDF]

, 2014
Neuroinflammation is a well-orchestrated, dynamic, multicellular process playing a major role in neurodegenerative disorders. The microglia which make up the innate immune system of the central nervous system are key cellular mediators of ...
Ory, Dieter, Celeb, Sofie, Celen, Sofie, Verbruggen, Alfons, Bormans, Guy   +4 more
core   +1 more source

Ultrasmall, elementary and highly translational nanoparticle X-ray contrast media from amphiphilic iodinated statistical copolymers

Acta Pharmaceutica Sinica B, 2023
To expand the single-dose duration over which noninvasive clinical and preclinical cancer imaging can be conducted with high sensitivity, and well-defined spatial and temporal resolutions, a facile strategy to prepare ultrasmall nanoparticulate X-ray ...
Lu Su, Kellie S. Dalby, Hannah Luehmann, Sussana A. Elkassih, Sangho Cho, Xun He, Lisa Detering, Yen-Nan Lin, Nari Kang, Dennis A. Moore, Richard Laforest, Guorong Sun, Yongjian Liu, Karen L. Wooley   +13 more
doaj   +1 more source

Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography [PDF]

, 2012
Preliminary investigation of the radioiodinated (S,S)-reboxetine analogue, 123I-INER, in baboons showed this tracer to have promise for imaging the noradrenaline transporter (NAT) using single photon emission computed tomography (SPECT).
Sutherland, A., Tamagnan, G., Jobson, N.K., Batis, J., Tavares, A.A.S., Nicola K. Jobson, Sally L. Pimlott, Jeffery Batis, Dewar, D., Gilles Tamagnan, Deborah Dewar, Pimlott, S.L., Seibyl, J., Olivier Barret, Barret, O., Andrew Sutherland, Adriana Alexandre S. Tavares, John Seibyl   +17 more
core   +1 more source

PET agents in dementia : an overview [PDF]

, 2021
: This article presents an overview of imaging agents for PET that have been applied for research and diagnostic purposes in patients affected by dementia. Classified by the target which the agents visualize, seven groups of tracers can be distinguished,
Dierckx, Rudi A.J.O., Dierckx, Rudi, van Waarde, Aren, Marcolini, Sofia, De Deyn, Peter, De Deyn, Peter Paul, van Waarde, Aren; id_orcid, Marcolini, Sofia; id_orcid   +7 more
core   +1 more source

Positron Emission Tomography Probes for Imaging Cytotoxic Immune Cells

Pharmaceutics, 2022
Non-invasive positron emission tomography (PET) imaging of immune cells is a powerful approach for monitoring the dynamics of immune cells in response to immunotherapy.
Ala Amgheib, Ruisi Fu, Eric O. Aboagye
doaj   +1 more source

Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer [PDF]

Theranostics, 2011
Les photosensibilisateurs à base de porphyrine sont des agents utiles pour la thérapie photodynamique (PDT) et l'imagerie par fluorescence du cancer. Les porphyrines sont également d'excellents chélateurs de métaux formant des métallocomplexes très stables, ce qui en fait des véhicules de livraison efficaces pour les radio-isotopes.
Jiyun Shi, Tracy Liu, Juan Chen, David Green, D. Jaffray, Brian C. Wilson, Fan Wang, Gang Zheng   +7 more
openaire   +2 more sources

Musculoskeletal Imaging and Contrast Agents

, 2021
Musculoskeletal (MSK) imaging is a radiological subspecialty about bones, joints, and associated soft tissues. In recent years, increasing technological advances, especially 7 T magnetic resonance imaging (MRI), have enabled MSK imaging with the ...
Ustabasioglu F.E., Fethi Emre Ustabasioglu   +1 more
core   +1 more source

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer [PDF]

Cancer Prevention Research, 2011
Abstract COX-2 is a major contributor to the inflammatory response and cancer progression so it is an important target for prevention and therapy. COX-2 is absent or expressed at low levels in most epithelial cells but is found at high levels in inflammatory lesions, and many premalignant and malignant tumors.
Md Jashim, Uddin, Brenda C, Crews, Kebreab, Ghebreselasie, Imran, Huda, Philip J, Kingsley, Mohammad Sib, Ansari, Mohammed N, Tantawy, Jeffery, Reese, Lawrence J, Marnett   +8 more
openaire   +2 more sources

[89Zr]Oxinate4 for long-term in vivo cell tracking by positron emission tomography [PDF]

, 2014
Purpose 111In (typically as [111In]oxinate3) is a gold standard radiolabel for cell tracking in humans by scintigraphy. A long half-life positron-emitting radiolabel to serve the same purpose using positron emission tomography (PET) has long been ...
Meszaros, L.K., James R. Ballinger, Gregory E. D. Mullen, Putthiporn Charoenphun, Charoenphun, Putthiporn, chuamsaamarkkee, k, Ferris, Trevor J, Trevor J. Ferris, ballinger, J.R., Chuamsaamarkkee, Krisanat, Went, Michael J, Meszaros, Levente K, Sharif-Paghaleh, Ehsan, Charoenphun, P., Krisanat Chuamsaamarkkee, Sharif-Paghaleh, e, Blower, Philip J., Mullen, Gregory E. D., Philip J. Blower, Mullen, Gregory E D, Blower, Philip J, Levente K. Meszaros, Ferris, T.J., Ehsan Sharif-Paghaleh, Went, Michael J., Michael J. Went, Ballinger, James R   +26 more
core   +1 more source