Results 41 to 50 of about 110,621 (200)

A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics

open access: yesPharmaceutics, 2019
Porphyrins are known therapeutic agents for photodynamic therapy of cancer and also imaging agents for NIR fluorescence imaging, MRI, or PET. A combination of interesting features makes tetrapyrrolic macrocycles suitable for use as theranostic agents ...
Bruno F. O. Nascimento   +4 more
doaj   +1 more source

Prostate Cancer—PET Imaging Update

open access: yes, 2023
Prostate cancer is the most common non-dermatologic cancer in men, and one of the leading causes of cancer-related mortality. The incidence of prostate cancer increases precipitously after the age of 65 and demonstrates variable aggressiveness, depending
Gupta, Akshya   +11 more
core   +1 more source

Metal-Based Complexes as Pharmaceuticals for Molecular Imaging of the Liver

open access: yesPharmaceuticals, 2019
This article reviews the use of metal complexes as contrast agents (CA) and radiopharmaceuticals for the anatomical and functional imaging of the liver.
Julia Greiser   +2 more
doaj   +1 more source

Development of a 68Ga-Fluorinated Porphyrin Complex as a Possible PET Imaging Agent [PDF]

open access: yesNuclear Medicine and Molecular Imaging, 2011
Due to the interesting pharmacologic properties of porphyrins, the idea of developing a possible tumor imaging agent using PET by incorporating (68)Ga into a suitable porphyrin ligand was investigated.(68)Ga-labeled 5,10,15,20-tetrakis(pentafluoro-13 phenyl) porphyrin ((68)Ga-TFPP) was prepared using freshly eluted [(68)Ga]GaCl3 obtained from a 68Ge ...
Yousef, Fazaeli   +7 more
openaire   +2 more sources

Artificial tissue binding models : development and comparative evaluation of high - throughput lipophilicity assays and their use for PET tracer optimization [PDF]

open access: yes, 2015
The purpose of this thesis was to increase the efficiency of the Positron Emission Tomography (PET) tracer development process. Since many neuroimaging agents fail due to undesirably high non-specific binding (NSB) to brain tissue, we aimed at estimating
Assmus, Frauke
core   +1 more source

Update on the Use of PET/MRI Contrast Agents and Tracers in Brain Oncology: A Systematic Review

open access: yesInternational Journal of Nanomedicine, 2022
Alessio Smeraldo,1– 3,* Alfonso Maria Ponsiglione,1,* Andrea Soricelli,4 Paolo Antonio Netti,1– 3 Enza Torino1– 3 1Department of Chemical, Materials and Production Engineering, University of Naples “Federico II”, Naples, 80125, Italy ...
Smeraldo A   +4 more
doaj  

Amyloid tracers detect multple binding sites in Alzheimer´s disease brain tissue. [PDF]

open access: yes, 2013
Imaging fibrillar amyloid-β deposition in the human brain in vivo by positron emission tomography has improved our understanding of the time course of amyloid-β pathology in Alzheimer’s disease. The most widely used amyloid-β imaging tracer so far is 11C-
Nordberg, A,   +9 more
core   +1 more source

Radiolabeled Iron Oxide Nanoparticles as Dual Modality Contrast Agents in SPECT/MRI and PET/MRI

open access: yesNanomaterials, 2023
During the last decades, the utilization of imaging modalities such as single photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI) in every day clinical practice has enabled clinicians to ...
Maria-Argyro Karageorgou   +3 more
doaj   +1 more source

Conscious rat PET imaging with soft immobilization for quantitation of brain functions: comprehensive assessment of anesthesia effects on cerebral blood flow and metabolism

open access: yesEJNMMI Research, 2021
Background Animal brain functions evaluated by in vivo imaging under anesthesia can be affected by anesthetic agents, resulting in incorrect assessment of physiological brain function.
Chie Suzuki   +2 more
doaj   +1 more source

Review article liver metastases

open access: yesJournal of the Belgian Society of Radiology, 2011
Liver metastases are a very common site of distant metastases. Detection and accurate characterization of liver metastases is of importance to guide therapy.
W Schima   +3 more
doaj   +1 more source

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