Results 191 to 200 of about 449,349 (233)

Radiolabelling and evaluation of novel haloethylsulfoxides as PET imaging agents for tumor hypoxia

Nuclear Medicine and Biology, 2012
The significance of imaging hypoxia with the PET ligand [(18)F]FMISO has been demonstrated in a variety of cancers. However, the slow kinetics of [(18)F]FMISO require a 2-h delay between tracer administration and patient scanning. Labelled chloroethyl sulfoxides have shown faster kinetics and higher contrast than [(18)F]FMISO in a rat model of ischemic
Evelyn, Laurens, Shinn Dee, Yeoh, Angela, Rigopoulos, Diana, Cao, Glenn A, Cartwright, Graeme J, O'Keefe, Henri J, Tochon-Danguy, Jonathan M, White, Andrew M, Scott, Uwe, Ackermann   +9 more
openaire   +2 more sources

QSAR modeling of PET imaging agents for the diagnosis of Parkinson’s disease targeting dopamine receptor

Theoretical Chemistry accounts, 2020
P. De, K. Roy
semanticscholar   +1 more source

Copper and Gallium PET Imaging Agents for Applications in HIV and Cancer

2021
Positron emission tomography (PET) is a sensitive nuclear imaging technique that can highlight physiological and biochemical processes in vivo. If we extend the current utility of PET, we can both diagnose disease earlier, and improve our understanding of disease evolution. This thesis represents an investigation into PET applications in HIV and cancer,
openaire   +2 more sources

PET brain imaging in neurological disorders.

Physics of Life Reviews
Brain disorders are a series of conditions with damage or loss of neurons, such as Parkinson's disease (PD), Alzheimer's disease (AD), or drug dependence.
Lijun Xie, Jihua Zhao, Ye Li, Jie Bai
semanticscholar   +1 more source

WITHDRAWN:New PET imaging agents in the management of solid cancers.

Current opinion in oncology
Ahead of Print article withdrawn by publisher.
Camilo, Garcia, Geraldine, Gebhart, Patrick, Flamen   +2 more
openaire   +1 more source

A facile synthesis of beta-amyloid PET imaging agent [18F]Florbetaben

Nuclear Medicine and Biology, 2022
Hari Akula, Doyoung Noh, Bao Hu, Yiu-Fung Mui, Ramin Parsey, Mark Slifstein, Wenchao Qu   +6 more
openaire   +1 more source

F-18 Polyethyleneglycol stilbenes as PET imaging agents targeting Abeta aggregates in the brain.

Nuclear Medicine and Biology, 2005
Wei Zhang, S. Oya, M. Kung, C. Hou, D. Maier, H. Kung   +5 more
semanticscholar   +1 more source

Preparation and evaluation of 17-ethynyl-substituted 16 alpha-[18F]fluoroestradiols: selective receptor-based PET imaging agents.

International Journal of Radiation Applications and Instrumentation Part B Nuclear Medicine and Biology, 1992
H. VanBrocklin, M. Pomper, K. Carlson, M. Welch, J. Katzenellenbogen   +4 more
semanticscholar   +1 more source

Comparative analysis of folate derived PET imaging agents with [(18)F]-2-fluoro-2-deoxy-d-glucose using a rodent inflammatory paw model.

Molecular Pharmaceutics, 2013
S. Kularatne, M. Bélanger, Xiangjun Meng, Brett Connolly, Amy Vanko, D. Suresch, I. Guenther, Shubing Wang, P. Low, P. Mcquade, Dinko Gonzalez Trotter   +10 more
semanticscholar   +1 more source

Synthesis and biological evaluation of a series of novel N- or O-fluoroalkyl derivatives of tropane: potential positron emission tomography (PET) imaging agents for the dopamine transporter.

Bioorganic & Medicinal Chemistry Letters, 2001
X. Gu, R. Zong, N. Kula, R. Baldessarini, J. Neumeyer   +4 more
semanticscholar   +1 more source