Results 71 to 80 of about 416,778 (248)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Fabricación de ladrillos a base de polímeros PET y virutas metálicas

Revista de Iniciación Científica, 2018
En este artículo se plantea la fabricación de ladrillos de plástico fundido con virutas producto del mecanizado como un elemento constructivo. En este trabajo el material utilizado es el polietileno de tereftalato, mejor conocido como PET.
José Luis Maure, María Candanedo, Jeancarlos Madrid, Marco Bolobosky, Nacarí Marín   +4 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Laboratory Studies on the Production of Asphalt Mixture Bad 22,4 with Pet (Plastic Bottle Fibers)

Romanian Journal of Transport Infrastructure
Plastic is a versatile and cheap material, but extremely durable and nearly impossible to decompose in nature. Plastic waste is not only a visual pollution issue but also a global health problem, as microplastics enter the food chain, affecting both ...
Claudiu-Ionel Chicuș, Gheorghe Gugiuman, Gelu-Răzvan Gimiga, Cristian Iriciuc Silviu   +3 more
doaj   +1 more source

The Research Progress of Monoclonal Antibody Labeled with 89Zr

Journal of Isotopes
Zirconium-89 (89Zr) is a metallic positron-emitting radionuclide. The relatively long half-life and moderate energy making 89Zr especially suitable for the labeling of large biomolecules such as antibodies for radioimmuno-PET (positron emission ...
Zhanxiong XIAO, Fei DUAN, Hongyu LI
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Kassi helge kuju eesti rahvapärimuses [PDF]

Mäetagused, 2007
The article opens with an overview about the extremely positive image of the cat in contemporary Estonian media, but also about the considerably more ambivalent image familiar from modern beliefs, truisms, narrative sequels, and comparisons. Some truisms
Kristi Salve
doaj  

Singular value decomposition analysis of back projection operator of maximum likelihood expectation maximization PET image reconstruction

Radiology and Oncology, 2018
In emission tomography maximum likelihood expectation maximization reconstruction technique has replaced the analytical approaches in several applications.
Somai Vencel, Legrady David, Tolnai Gabor   +2 more
doaj   +1 more source