Results 71 to 80 of about 570,057 (299)

Laboratory Studies on the Production of Asphalt Mixture Bad 22,4 with Pet (Plastic Bottle Fibers)

Romanian Journal of Transport Infrastructure
Plastic is a versatile and cheap material, but extremely durable and nearly impossible to decompose in nature. Plastic waste is not only a visual pollution issue but also a global health problem, as microplastics enter the food chain, affecting both ...
Claudiu-Ionel Chicuș, Gheorghe Gugiuman, Gelu-Răzvan Gimiga, Cristian Iriciuc Silviu   +3 more
doaj   +1 more source

Fluorinated phenylalanines: synthesis and pharmaceutical applications

Beilstein Journal of Organic Chemistry, 2020
Recent advances in the chemistry of peptides containing fluorinated phenylalanines (Phe) represents a hot topic in drug research over the last few decades.
Laila F. Awad, Mohammed Salah Ayoup
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Hospitality on a Leash: A Study of the Online Visibility, Availability and Distribution of Pet-friendly Accommodations in Romania

Studia Universitatis Babeş-Bolyai: Geographia
Hospitality on a Leash: a Study of the Online Visibility, Availability and Distribution of Pet-Friendly Accommodations in Romania. The present paper explores the growing phenomenon of pet travel within contemporary tourism, focusing on the preferences ...
Gabriela MUNTEANU
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Improving mechanical properties of recycled fibre-reinforced concrete through the use of magnetic water

Advances in Civil and Architectural Engineering
This study investigated the performance of Polyethylene terephthalate (PET), polypropylene, and steel fibres in concrete, utilizing both regular and magnetic water.
Mahdi Jangi, Amin Honarbakhsh, Davoud Tavakoli   +2 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

People and Pets in the COVID-19 Pandemic and the Cost-of-Living Crisis: Identifying Trends in the Intake, Adoption and Return of Companion Animals During Times of Uncertainty

Animals
Pet ownership is the most common form of human–animal interaction (HAI), is prevalent worldwide and confers benefits for the health and wellbeing of humans.
Lindsay Murray, Janine Carroll, Jane Tyson   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source