Results 121 to 130 of about 6,004 (229)

α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes.

PLoS Pathogens, 2015
Rosetting, the adhesion of Plasmodium falciparum-infected erythrocytes to uninfected erythrocytes, involves clonal variants of the parasite protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) and soluble serum factors. While rosetting is a well-
Liz Stevenson, Erik Laursen, Graeme J Cowan, Betty Bandoh, Lea Barfod, David R Cavanagh, Gregers R Andersen, Lars Hviid   +7 more
doaj   +1 more source

Optimized Expression Condition of CIDRα-PfEMP1 Recombinant Protein Production in Escherichia coli BL21(DE3): A Step to Develop Malaria Vaccine Candidate

, 2021
Winnie Almira Setyoadji, Sulistyaningsih Sulistyaningsih, Irawan Fajar Kusuma   +2 more
openalex   +2 more sources

Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein

, 2021
Natalie M. Barber, Clinton K. Lau, Louise Turner, G. M. Watson, Susan Thrane, John Lusingu, Thomas Lavstsen, Matthew K. Higgins   +7 more
openalex   +1 more source

Rosette-mediating PfEMP1 variants: conservation and strain-transcending antibodies

, 2022
Plasmodium falciparum malaria is one of the leading causes of child mortality worldwide, and currently there is no vaccine which confers sterilising immunity against infection. One approach to reducing the morbidity and mortality associated with P. falciparum malaria would be the development of a vaccine which targets P.
openaire   +2 more sources

Plasmodium falciparum PfEMP1 Modulates Monocyte/Macrophage Transcription Factor Activation and Cytokine and Chemokine Responses [PDF]

, 2017
Natália G. Sampaio, Emily M. Eriksson, Louis Schofield   +2 more
openalex   +1 more source

Red blood cell polymorphisms and adaptation to malaria [PDF]

, 2009
Malarija je zarazna bolest koju uzrokuju paraziti iz roda Plasmodium, a prenose je komarci iz roda Anopheles. Mortalitet je dosta visok unatoč postojanju lijekova protiv malarije jer si ljudi koji žive u područjima s endemičnom malarijom često ne mogu ...
Puhović, Jasmina
core   +2 more sources

Mosaic and cocktail capsid-virus-like particle vaccines for induction of antibodies against the EPCR-binding CIDRα1 domain of PfEMP1 [PDF]

Ilary Riedmiller, Cyrielle Fougeroux, Rasmus W. Jensen, Ikhlaq Hussain Kana, Adam F. Sander, Thor G. Theander, Thomas Lavstsen, Louise Turner   +7 more
openalex   +3 more sources

Serum Lipoproteins Promote Efficient Presentation of the Malaria Virulence Protein PfEMP1 at the Erythrocyte Surface

, 2007
Sarah Frankland, Salenna R. Elliott, Francisca Yosaatmadja, James G. Beeson, Stephen J. Rogerson, Akinola Adisa, Leann Tilley   +6 more
openalex   +1 more source

Plasmodium knowlesi: a superb in vivo nonhuman primate model of antigenic variation in malaria. [PDF]

, 2018
Antigenic variation in malaria was discovered in Plasmodium knowlesi studies involving longitudinal infections of rhesus macaques (M. mulatta). The variant proteins, known as the P. knowlesi Schizont Infected Cell Agglutination (SICA) antigens and the P.
Ay, F, Fonseca, LL, Galinski, MR, Joyner, CJ, Lapp, SA, LE Roch, KG, MAHPIC CONSORTIUM, Peterson, MS, Voit, EO   +8 more
core  

PfEMP1-DBL1α amino acid motifs in severe disease states of Plasmodium falciparum malaria

, 2007
Johan Normark, Daniel Nilsson, Ulf Ribacke, Gerhard Winter, Kirsten Moll, Craig E. Wheelock, Justus Bayarugaba, Fred Kironde, Thomas G. Egwang, Qijun Chen, Björn Andersson, Mats Wahlgren   +11 more
openalex   +1 more source