Results 121 to 130 of about 33,493 (201)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Inhibition of TWEAK/Fn14 Ameliorates Sarcopenic Obesity by Restoring Mitochondrial Biogenesis via the AMPK/SIRT1/PGC-1α Axis. [PDF]

Diabetes Metab Syndr Obes
Xuekelati S, Maimaitiwusiman Z, Guo Y, Guo S, Xu Q, Ke J, Xu L, Yang Y, Wang H.   +8 more
europepmc   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source

PGC-1α protects against MASH via Tim23-dependent inhibition of DRP1-mediated ferroptosis. [PDF]

Cell Death Dis
Zhao Y, Zhang L, Li B, Liu M, Zhang Y, Li T, Ning S, Zhang X.   +7 more
europepmc   +1 more source

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway, Peter J. Ferrandi, Hector G. Paez, Christopher R. Pitzer, Junaith S. Mohamed, Michael R. Deschenes, James A. Carson   +6 more
wiley   +1 more source

Sprint‐interval training with post‐exercise blood flow restriction increases mitochondrial content and respiration

The Journal of Physiology, EarlyView.
Abstract figure legend The mechanisms underpinning improved maximal oxygen uptake following sprint interval training (SIT) with post‐exercise blood flow restriction (BFR), compared to SIT alone, remain unclear. This study examined the effects of 6 week SIT with (BFR; n = 12) or without (CON; n = 8) post‐exercise BFR on V̇O2peak${{\dot{V}}_{{{{\mathrm{O}
Donald L. Peden, Carolin Stangier, Emma A. Mitchell, Stephen J. Bailey, Richard A. Ferguson   +4 more
wiley   +1 more source

<i>Porphyromonas gingivalis</i> Promotes Neuroinflammation by Microglial Ferroptosis via NOX4/PPAR-α/PGC-1α Pathway. [PDF]

Research (Wash D C)
Li X, Wu Z, Yao C, Zhang P, Zhu Q, Nan S, Xiao L, Qi S.   +7 more
europepmc   +1 more source

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu, Boya Ouyang, Yi Yuan, Jesus Simal‐Gandara, Hui Cao   +4 more
wiley   +1 more source

Basal Energetics and Phosphocreatine Recovery Kinetics in Ambulatory Boys With Duchenne Muscular Dystrophy

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Basal energetics and phosphocreatine (PCr) recovery kinetics of the lower leg anterior compartment (primarily tibialis anterior; TA) were evaluated at rest and after dorsiflexion muscle contractions in ambulatory boys with Duchenne muscular dystrophy (DMD) and unaffected controls using 31P‐MRS.
Pratiksha P. Awale, Christophor Lopez, Tanja Taivassalo, Krista Vandenborne, Glenn A. Walter, Sean C. Forbes   +5 more
wiley   +1 more source

Esculetin Improves LPS/D-GalN Induced Acute Liver Injury Through AMPK/SIRT1/PGC-1α Signaling Pathway. [PDF]

Antioxidants (Basel)
Dai H, Zhang Q, Chen P, Chen S.
europepmc   +1 more source