Food Frontiers, EarlyView.HH inhibits the androgen/AR and TGF‐β1/Smad signaling pathways, and may offer a novel therapeutic approach for BPH treatment. ABSTRACT Benign prostate hyperplasia (BPH) is characterized by abnormal prostate epithelial and stromal cell growth, which leads to bladder outlet obstruction (BOO) and lower urinary tract symptoms (LUTS).
Buyun Kim +11 more
wiley +1 more source
Fungal Symbionts Produce Prostaglandin E2 to Promote Their Intestinal Colonization
Frontiers in Cellular and Infection Microbiology, 2019 Candida albicans is a ubiquitous fungal symbiont that resides on diverse human barrier surfaces. Both mammalian and fungal cells can convert arachidonic acid into the lipid mediator, prostaglandin E2 (PGE2), but the physiological significance of fungus ...
Tze Guan Tan +4 more
doaj +1 more source
1078 EFFECT OF PGE2 (P) ON NEONATAL RENAL FUNCTION [PDF]
, 1978 E G John +4 more
openalex +1 more source
PGE2 Elevates IL-23 Production in Human Dendritic Cells via a cAMP Dependent Pathway
Mediators of Inflammation, 2015 PGE2 elevates IL-23 production in mouse dendritic cells while inhibits IL-23 production in isolated human monocytes. Whether this differential effect of PGE2 on IL-23 production is cell-type- or species-specific has not been investigated in detail.
Quanxing Shi +7 more
doaj +1 more source
Transforming growth factor-beta stimulation of lung fibroblast prostaglandin E2 production. [PDF]
, 1989 Transforming growth factor-beta (TGF beta) stimulated the production of total protein, collagen, and fibronectin by normal human lung fibroblasts.
Diaz, Arturo +2 more
core +1 more source
TNF and PGE2 in human monocyte-derived macrophages infected with Chlamydia trachomatis
Mediators of Inflammation, 1993 In this study levels of prostaglandin E2 (PGE2), tumour necrosis factor (TNF) and interleukin-1 (IL-1) alpha in medium from monocyte derived macrophages (MdM) infected with Chlamydia trachomatis (L2/434/Bu or K biovars).
E. Manor, E. Schmitz, I. Sarov
doaj +1 more source
Regulation of Dendritic Cell Function by Ermiaosan via the EP4-cAMP-CREB Signaling Pathway [PDF]
arXivErmiao San (EMS), a traditional Chinese medicine composed of Atractylodes macrocephala and Cortex Phellodendron, has demonstrated therapeutic efficacy in rheumatoid arthritis (RA). Studies suggest that EMS modulates dendritic cell (DC) maturation in adjuvant arthritis (AA) rats, though the precise mechanisms remain unclear.
arxiv
Effects of sulphasalazine and disodium azodisalicylate on colonic PGE2 concentrations determined by equilibrium in vivo dialysis of faeces in patients with ulcerative colitis and healthy controls. [PDF]
, 1984 K. Lauritsen +4 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) may improve survival in certain types of cancer, but evidence has been inconclusive so far regarding their effect on endometrial cancer survival. Here, the authors present data from a large population‐based cohort study in Norway, including 7751 individuals with endometrial ...
Ala Jabri Haug +6 more
wiley +1 more source
Regulation by Fc fragments of the secretion of collagenase, PGE2, and lysozyme by mouse peritoneal macrophages. [PDF]
, 1980 J H Passwell +3 more
openalex +1 more source