Results 261 to 270 of about 133,795 (342)

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

The COX Pathway Alters Hematopoiesis in Hashimoto's Thyroiditis. [PDF]

Cells
Wrońska K, Ziętek M, Marciniak M, Szczuko M.   +3 more
europepmc   +1 more source

Comparison of Prostaglandin E2 (PGE2) in Salivary Gland of Boophilus microplus, Haemaphysalis longicornis and Ixodes holocyclus, and Quantification of PGE2 in Saliva, Hemolymph, Ovary and Gut of B. microplus.

, 1994
Hisashi INOKUMA, D. H. Kemp, Peter Willadsen   +2 more
openalex   +2 more sources

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

IL-1β⁺ tumor-associated macrophages accelerate glioblastoma progression by amplifying the PGE2-EP4 signaling. [PDF]

J Neuroinflammation
Liang H, Yang Q, Zhong B, Li D, Wu F, Zhang J, Guo C, Zhu Z, Feng M, Zhang Y, Peng H.   +10 more
europepmc   +1 more source

PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice

, 2015
He Wu, Tao Wu, Hua Wei, Xianghui Dong, Yufeng Gao, Xiaochun Zhao, Wenwu Chen, Wangsen Cao, Qingwu Yang, Jiping Qi, Jin Zhou, Jian Wang   +11 more
openalex   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Characterization of a new specific mPGES-1 inhibitor in cardiovascular system. [PDF]

Sci Rep
Lin X, Feng H, Zhang JR, Gurusamy M, Nasseri S, Pekcec A, Wu D.   +6 more
europepmc   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Nuclear factor erythroid 2-related factor 2/heme oxygenase-1 activation by nattokinase reduces pro-inflammatory and matrix-degrading mediators in human gingival fibroblasts. [PDF]

J Dent Sci
Li YL, Wu YC, Tseng CF, Wang YL, Li SY, Tien Vo TT, Chen YL, Shih YT, Lee IT.   +8 more
europepmc   +1 more source