Results 31 to 40 of about 122,171 (336)
Aim and Background: Anti-inflammatory compounds are effective in improving the symptoms of inflammatory bowel diseases such as ulcerative colitis. The aim of this study was to evaluate the effect of aloe vera extract against the inflammatory factors ...
zakieh keshavarzi+3 more
doaj
Granulosa cell proliferation is inhibited by PGE2 in the primate ovulatory follicle
Prostaglandin E2 (PGE2) is a key paracrine mediator of ovulation. Few specific PGE2-regulated gene products have been identified, so we hypothesized that PGE2 may regulate the expression and/or activity of a network of proteins to promote ovulation.
Patric S. Lundberg+5 more
doaj +1 more source
Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production. [PDF]
Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to protect neuronal cells in a variety of pathophysiological situations including Alzheimer's disease ...
Akundi, Ravi S.+7 more
core +1 more source
Role of a cyclooxygenase-2 cascade in breast cancer cell dissemination
Current therapeutic approaches based on a study of the genetic portrait of a tumor individualize treatment policy to a greater extent, which cre- ates real prospects for the increasing number of patients to recover.
M. A. Taipov+4 more
doaj +1 more source
Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G+8 more
core +1 more source
Pge2 Accelerates Myogenesis of C2c12 Myoblasts [PDF]
Prostaglandin E2 (PGE2), a modulator of physiological responses including inflammation, fever, and smooth muscle tone, is a prostanoid synthesized from arachidonic acid via the cyclooxygenase pathway.PGE2 is released in large amounts by injured muscle fibers, and is linked to muscle regeneration by regulating myoblast fusion. However, the physiological
Marco Brotto+2 more
openaire +2 more sources
In this work, we demonstrated that PUM70 specifically suppressed LPS‐mediated inflammatory responses. Notably, PUM70 treatment inhibited LPS‐induced lung damage, pro‐inflammatory cytokine production, and reduced macrophage infiltration in the lungs. Mechanistically, PUM70 suppressed LPS‐induced inflammation and oxidative stress via the Nrf2/HO‐1 and ...
Fei Peng, Xin Ren, Bin Du, Yuedong Yang
wiley +1 more source
Objective: This study aims to evaluate the effect of low-level laser therapy on peri-miniscrew fluid prostaglandin E2 (PGE2) and substance P (SP) levels during orthodontic treatment.Methods: A total of 15 individuals were included in this study ...
Özer Alkan+3 more
doaj +1 more source
The role of PGE2 in intestinal inflammation and tumorigenesis [PDF]
Release of the free fatty acid arachidonic acid (AA) by cytoplasmic phospholipase A2 (cPLA2) and its subsequent metabolism by the cyclooxygenase and lipoxygenase enzymes produces a broad panel of eicosanoids including prostaglandins (PGs). This study sought to investigate the roles of these mediators in experimental models of inflammation and ...
Anthony T. Vella+6 more
openaire +3 more sources
Following oral administration of arthrocen supplement in post‐stroke depression model, the study recommended a novel protective effect by arthrocen on neuroinflammation due to stroke. It may play an antidepressant role through anti‐inflammatory as well as improved activity and mobility in mice‐induced stroke.
Ramin Goudarzi+5 more
wiley +1 more source