Results 21 to 30 of about 89,482 (299)

Reduction of voluntary physical activity in mice induced by toll-like receptor 7 agonist R-848

Journal of Physical Fitness and Sports Medicine, 2018
The behavioral response of mice to infection is often demonstrated by a reduction in physical activity. Although it is known that single-stranded (ss) RNA, one of the genomes found in viruses, activates to produce type I interferon (IFNs) and pro ...
Eri Oyanagi, Masataka Uchida, Michael J. Kremenik, Hiromi Yano   +3 more
doaj   +1 more source

Effect of Low-Level Laser Therapy on Peri-Miniscrew Fluid Prostaglandin E2 and Substance P Levels: A Controlled Clinical Trial

Turkish Journal of Orthodontics, 2021
Objective: This study aims to evaluate the effect of low-level laser therapy on peri-miniscrew fluid prostaglandin E2 (PGE2) and substance P (SP) levels during orthodontic treatment.Methods: A total of 15 individuals were included in this study ...
Özer Alkan, Yeşim Kaya, Esra Yüksek, Ahmet Ufuk Kömüroglu   +3 more
doaj   +1 more source

Upregulation of prostaglandin E by inducible microsomal prostaglandin E synthase-1 in colon cancer [PDF]

Annals of Coloproctology, 2022
Purpose Prostaglandin E2 (PGE2) is known to promote carcinogenesis and cancer progression in colon cancer. Enzymes involved in the metabolism of PGE2 include cyclooxygenase (COX)-2, microsomal prostaglandin E synthase-1 (mPGES-1), and 15-prostaglandin ...
Young Hun Kim, Kyung Jong Kim
doaj   +1 more source

Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ : prostaglandin E2 dependent proliferation of growth plate chondrocytes [PDF]

, 2006
Prostaglandin E2 (PGE2) plays an important role in bone development and metabolism. To interfere therapeutically in the PGE2 pathway, however, knowledge about the involved enzymes (cyclooxygenases) and receptors (PGE2 receptors) is essential.
Nüsing, Rolf M., Neuland, Pia, Brochhausen, Christoph, Rolf M Nüsing, Günter Klaus, Kirkpatrick, Charles James, Christoph Brochhausen, Klaus, Günter, Pia Neuland, C James Kirkpatrick   +9 more
core   +1 more source

Influence of polychlorinated biphenyls (PCBs) and phytoestrogens on prostaglandin F2α and E2secretion from bovine endometrial cells at a postovulatory stage of the estrous cycle

Veterinární Medicína, 2005
Polychlorinated biphenyls (PCBs) and phytoestrogens were found to affect contractions of bovine uterus. Prostaglandins (PG) F2á and E2 are also involved in the uterine contractility.
M. Wrobel, J. Kotwica
doaj   +1 more source

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Geisslinger, Gerd, Rolf M. Nusing, Gerd Geisslinger, Scholich, Klaus, Angioni, Carlo Federico, Klaus Scholich, Laura Popp, Brenneis, Christian, Ovidiu Coste, Becker, Wiebke, Popp, Laura, Nusing, Rolf M., Coste, Ovidiu, Carlo Angioni, Christian Brenneis, Ronald Schmidt, Wiebke Becker, Schmidt, Ronald   +17 more
core   +1 more source

Table_1_Lipopolysaccharide-induced immune stress negatively regulates broiler chicken growth via the COX-2-PGE2-EP4 signaling pathway.docx

, 2023
AimsImmune stress in broiler chickens is characterized by the development of persistent pro-inflammatory responses that contribute to degradation of production performance.
Yi Zhang (9093), Bingkun Zhang (417313), Koichi Ito, Kexin Liu, Wenrui Zhen, Xianglong He, Xianglong He (10531647), Dongying Bai (564525), Dongying Bai, Yi Zhang, Yuqian Li (577378), Yanbo Ma (11849240), Kexin Liu (1547230), Yanhao Liu (11786900), Koichi Ito (497958), Haiqiu Tan, Yanbo Ma, Haiqiu Tan (15393215), Yuqian Li, Bingkun Zhang, Wenrui Zhen (11849234), Yanhao Liu   +21 more
core   +1 more source

Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells

OncoImmunology, 2021
Prostaglandin E2 (PGE2), an arachidonic acid pathway metabolite produced by cyclooxygenase (COX)-1/2, has been shown to impair anti-tumor immunity through engagement with one or more E-type prostanoid receptors (EP1-4). Specific targeting of EP receptors,
Yun Wang, Long Cui, Peter Georgiev, Latika Singh, Yanyan Zheng, Ying Yu, Jeff Grein, Chunsheng Zhang, Eric S. Muise, David L. Sloman, Heidi Ferguson, Hongshi Yu, Cristina St. Pierre, Pranal J Dakle, Vincenzo Pucci, James Baker, Andrey Loboda, Doug Linn, Christopher Brynczka, Doug Wilson, Brian B Haines, Brian Long, Richard Wnek, Svetlana Sadekova, Michael Rosenzweig, Andrew Haidle, Yongxin Han, Sheila H. Ranganath   +27 more
doaj   +1 more source

Estradiol-induced immune suppression via prostaglandin E2 during parturition in bovine leukemia virus-infected cattle

PLoS ONE, 2022
Immune suppression during pregnancy and parturition is considered a risk factor that is related to the progression of bovine chronic diseases, such as bovine leukosis, which is caused by bovine leukemia virus (BLV). Our previous studies have demonstrated
Yamato Sajiki, Satoru Konnai, Tomohiro Okagawa, Naoya Maekawa, Shinya Goto, Junko Kohara, Atsushi Nitanai, Hirofumi Takahashi, Kentaro Kubota, Hiroshi Takeda, Shiro Murata, Kazuhiko Ohashi   +11 more
doaj   +2 more sources

Brazilian medicinal plants with corroborated anti-inflammatory activities: a review

Pharmaceutical Biology, 2018
Context: Inflammatory disorders are common in modern life, and medicinal plants provide an interesting source for new compounds bearing anti-inflammatory properties.
Victor Pena Ribeiro, Caroline Arruda, Mohamed Abd El-Salam, Jairo Kenupp Bastos   +3 more
doaj   +1 more source