Results 71 to 80 of about 5,754 (180)

Preimplantation genetic testing for four families with severe combined immunodeficiency: Three unaffected livebirths

Orphanet Journal of Rare Diseases
Purpose Severe combined immunodeficiency (SCID) is a set of rare monogenic inherited diseases that together represent the most severe form of the primary immunodeficiency disease phenotype. Preimplantation genetic testing for monogenic defects (PGT-M) is
Lingyun Zhang, Lei Feng, Hao Shi, Wenbin Niu, Yanchi Wang, Bei Bu, Yidong Liu, Xiao Bao, Wenyan Song, Haixia Jin, Yingpu Sun   +10 more
doaj   +1 more source

Pregnancy Outcomes and Postnatal Health From Transferred Mosaic Embryos Following Preimplantation Genetic Testing for Aneuploidy

iNew Medicine, Volume 2, Issue 2, June 2026.
This illustration synthesizes the methods and conclusion of this study, demonstrating that the transfer of mosaic embryos following reimplantation genetic testing for aneuploidy does not increase the risk to postnatal health. ABSTRACT Next‐generation sequencing (NGS) has increased the detection of mosaic embryos during preimplantation genetic testing ...
Lili Chen, Dehuan Huang, Jingcheng Sang, Yiqi Yin, Caiyun Wu, Yan Hao, Dawei Chen, Zhiguo Zhang, Yunxia Cao, Ri‐Cheng Chian, Ping Zhou   +10 more
wiley   +1 more source

Barriers and facilitators to genetic counseling service availability in the Arab world: A genetic counselors' perspective

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Despite the global growth of the genetic counseling field, many Arab countries either lack genetic services or have limited resources restricted to specific specialties. This qualitative study is among the first to explore genetic counselors' (GCs) perspectives on challenges and facilitators to the field in Arab countries.
Batoul Elbassiouny, Rawan Awwad, Carla I. Campbell, Pranathi Kandikonda, Hossein Nazari, Ian M. MacFarlane   +5 more
wiley   +1 more source

A big step forward for PGT-M? [PDF]

Reproductive BioMedicine Online, 2018
Sharyn, Stock-Myer, Martin, Johnson
openaire   +2 more sources

TRENDS IN PREIMPLANTATION GENETIC TESTING FOR MONOGENIC DISORDERS (PGT-M) [PDF]

Fertility and Sterility, 2021
Andria G. Besser, David H. McCulloh, Caroline McCaffrey, James A. Grifo   +3 more
openaire   +1 more source

Assessing the efficacy of targeted enrichment protocol in PGT-M applications: a comprehensive analysis

Journal of Assisted Reproduction and Genetics
The aim of this study is to assess whether the Targeted Sequence Enrichment (TSE) protocol improves the efficiency of Preimplantation Genetic Testing for Monogenic Diseases (PGT-M) by reducing allele dropout (ADO) rates.This retrospective data analysis included 928 patients and compared ADO rates across three different PGT-M approaches: (1 ...
Evrim Unsal, Leyla Ozer, Volkan Baltaci, Turker Duman, Cihan Halicigil, Zeynep Koc, Asli Belen Saglam, Pelin Buyuk, Sercan Baris, Suleyman Aktuna   +9 more
openaire   +3 more sources

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Systems of reciprocity in human–ocean relationships: Across time, place, language and culture

People and Nature, Volume 8, Issue 6, Page 1660-1675, June 2026.
Abstract In the face of large‐scale marine environmental challenges, solutions that meaningfully capture the complexity of socio‐cultural and economic factors contributing to such issues—and their solutions—are urgently needed. This scoping review explores examples of reciprocity in human–ocean relationships to inform the conceptual underpinning and ...
Kianna M. Gallagher, Rachel Kelly, Claire Konkes, Gretta T. Pecl   +3 more
wiley   +1 more source

Platform competition and strategic trade‐offs for complementors: Heterogeneous reactions to the entry of a new platform

Strategic Management Journal, Volume 47, Issue 6, Page 1671-1729, June 2026.
Abstract Research Summary We study how the entry of a rival platform affects the strategies of the incumbent's complementors. The latter face a trade‐off: While the entry threatens their benefits from indirect network effects, it also allows them to escape intense within‐platform competition.
Johannes Loh, Ambre Elsas‐Nicolle
wiley   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan, Mukesh Rathore, Dinesh Kumar Saini, Ayushi Singh, Naeela Qureshi, Nikita Aggarwal, Mahpara Bashir, Mehnaz Shakeel, Vikas Gupta, Sundeep Kumar, Rajeev Kumar Varshney, Reyazul Rouf Mir   +11 more
wiley   +1 more source