Results 81 to 90 of about 5,754 (180)

Discovering putative novel stem rust resistance loci in wheat genetic resources

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Stem rust (SR), caused by Puccinia graminis f. sp. tritici (Pgt), poses a threat to wheat production in Germany. This study evaluated 200 plant genetic resources (PGR) and 50 elite lines across four field environments. Multi‐environment genome‐wide association mapping based on PGR accessions revealed 1942 marker‐trait associations (MTAs ...
Jiaojiao Wang, Guoliang Li, Tim Kloppe, Kerstin Flath, Philipp Schulz, Mathias Wiegman, Thomas Miedaner, Yong Jiang, Jochen C. Reif   +8 more
wiley   +1 more source

Robust Preimplantation Genetic Testing Strategy for Myotonic Dystrophy Type 1 by Bidirectional Triplet-Primed Polymerase Chain Reaction Combined With Multi-microsatellite Haplotyping Following Whole-Genome Amplification

Frontiers in Genetics, 2019
Myotonic dystrophy type 1 (DM1) is caused by expansion of the DMPK CTG trinucleotide repeat. Disease transmission to offspring can be avoided through prenatal diagnosis or preimplantation genetic testing for monogenic disorders (PGT-M).
Mulias Lian, Caroline G. Lee, Caroline G. Lee, Caroline G. Lee, Samuel S. Chong, Samuel S. Chong, Samuel S. Chong   +6 more
doaj   +1 more source

Advances in gene cloning and functional genomics approaches for wheat (Triticum aestivum L.) improvement

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.) is a globally important cereal crop which provides ∼20% calories in human diet. Identifying genes and elucidating their functions is still challenging in wheat due to its large genome (∼16 Gb) with significant amount of repetitive elements.
Santosh Gudi, Khizar Razzaq, Jatinder Singh, Luis Del Rio Mendoza, Mohamed Khan, Rajeev Gupta, Upinder Gill   +6 more
wiley   +1 more source

Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testing

Nature Communications
High-throughput sequencing technologies have increasingly led to discovery of disease-causing genetic variants, primarily in postnatal multi-cell DNA samples.
Anouk E. J. Janssen, Rebekka M. Koeck, Rick Essers, Ping Cao, Wanwisa van Dijk, Marion Drüsedau, Jeroen Meekels, Burcu Yaldiz, Maartje van de Vorst, Bart de Koning, Debby M. E. I. Hellebrekers, Servi J. C. Stevens, Su Ming Sun, Malou Heijligers, Sonja A. de Munnik, Chris M. J. van Uum, Jelle Achten, Lars Hamers, Marjan Naghdi, Lisenka E. L. M. Vissers, Ron J. T. van Golde, Guido de Wert, Jos C. F. M. Dreesen, Christine de Die-Smulders, Edith Coonen, Han G. Brunner, Arthur van den Wijngaard, Aimee D. C. Paulussen, Masoud Zamani Esteki   +28 more
doaj   +1 more source

Predicting live birth following single euploid frozen‐embryo transfer via β‐hCG dynamics: iHOPE prognostic model with external validation

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 824-835, June 2026.
ABSTRACT Objectives To determine the prognostic value of serum β‐human chorionic gonadotropin (β‐hCG) for predicting live birth following single euploid frozen‐embryo transfer (FET), and to develop and validate a prognostic model (iHOPE) for this purpose. Methods This retrospective cohort study used data from two large fertility practices.
E. Kalafat, B. Ata, R. Del Gallego, A. Freedman, L. R. Hoyos, I. Elkhatib, K. A. Miller, H. Fatemi, B. Lawrenz   +8 more
wiley   +1 more source

Identity-by-state analysis: a new method for PGT-M [PDF]

Human Reproduction, 2020
openaire   +2 more sources

Case report: identification of novel variant in SLC26A2 gene and preimplantation genetic testing for monogenic disorders in preventing diastrophic dysplasia

Egyptian Journal of Medical Human Genetics
Background Diastrophic dysplasia is a rare autosomal recessive disorder characterized by abnormalities in bone and cartilage development, caused by pathogenic variants in the SLC26A2 gene.
Ziravard N. Tonyan, Yulia A. Nasykhova, Maria M. Danilova, Elena S. Shabanova, Olesya N. Bespalova, Igor Y. Kogan, Andrey S. Glotov   +6 more
doaj   +1 more source

Potential Flood Events in the Lower Missouri River Basin Over Multiple Centuries Identified Using Tree‐Ring Based Multi‐Model Streamflow Reconstructions

Water Resources Research, Volume 62, Issue 6, June 2026.
Abstract The Missouri River basin (MRB), the largest river basin in the United States, presents major water management challenges due to its complex topology and extensive infrastructure designed to manage high annual flows. Severe hydroclimatic events, particularly floods in 1993, 2011, and 2019, have highlighted vulnerabilities, leading the U.S. Army
Subhrendu Gangopadhyay, Edward R. Cook, Gregory T. Pederson, Connie A. Woodhouse, Gregory J. McCabe, Matthew P. Dannenberg, Victoria M. Harris, Erika K. Wise, Jeffrey P. Niehaus, Upmanu Lall   +9 more
wiley   +1 more source

PGT-M TO PREVENT 2 OR 3 GENETIC DISORDERS, MOSTLY DOMINANT [PDF]

Fertility and Sterility, 2021
Alexandra Peyser, Kristine McWilliams, Avner Hershlag   +2 more
openaire   +1 more source

A Practice Framework for Genetic Testing in Asymptomatic Relatives of Patients With Creutzfeldt‐Jakob Disease: Experience and Insights From Israel

European Journal of Neurology, Volume 33, Issue 6, June 2026.
Presymptomatic genetic testing for genetic Creutzfeldt‐Jakob disease requires careful balancing of autonomy, psychological preparedness, and potential familial implications. Based on multidisciplinary experience in Israel, we propose a structured framework including pre‐test counseling, psychological appraisal, genetic testing, in‐person results ...
Dror Shir, Noa Bregman, Aya Bar David, Talya Nathan, Orly Goldstein, Tanya Gurevich, Avner Thaler, Anat Mirelman, Tamara Shiner, Mali Gana Weisz, Shiri Shkedi‐Rafid, Gael Ganz, Hagit Shani, Elon Pras, Odelia Chorin, Gia Sorkin, Keren Markus‐Bustani, Shlomzion Kahana Merhavi, Mor Shechory‐Stahl, Miri Yanoov Sharav, Michal Dicastro, Dorin Trigubov, Dalit Barel, Esther Kahana, Avi Fellner, Amos Korczyn, Hagit Baris Feldman, Lior Greenbaum, Nurit Omer   +28 more
wiley   +1 more source