Results 151 to 160 of about 2,304,781 (175)
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Measurement of Intracellular pH
2003The activity of most cellular processes is sensitive to pH. Cells therefore tightly control cytosol pH within narrow bounds. Measurement of cytosolic pH is of interest in studying many processes, including pH regulatory transport proteins. Key approaches that have been used to determine intracellular pH include pH-sensitive microelectrodes, nuclear ...
Joseph R. Casey, Frederick B. Loiselle
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pH measurements in ultranarrow immobilized pH gradients
Journal of Biochemical and Biophysical Methods, 1986It is possible to measure pH values in immobilized pH gradients (IPG) when the polyacrylamide matrix is made to contain an additional, carrier ampholyte-generated pH gradient. After an IPG run, 5 mm gel segments, along the separation axis, are cut and eluted in 300 microliter of 10 mM KCl and the pH read with a standard pH meter. When using ultranarrow
Ermanna Rovida +3 more
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The High pH and pH-Shift Refolding Technology
Current Pharmaceutical Biotechnology, 2010We have developed a high-pH, pH-shift refolding "Ph-Fold technology", both for academic research and industrial protein drug development applications. Using this technology, we were able to refold some "difficult-to-refold" proteins, some of which are proven important drug targets and protein drug candidates. The technology is composed of the initial E.
Xinli Lin, Tomomi Umetsu
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2018
Acne is based on a complex, multifactorial pathophysiology beginning with a microcomedo. Comedogenesis involves follicular hyperproliferation and disturbed keratinization, hyperseborrhea and hyperplasia of sebaceous glands as well as disturbances in skin microbiome.
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Acne is based on a complex, multifactorial pathophysiology beginning with a microcomedo. Comedogenesis involves follicular hyperproliferation and disturbed keratinization, hyperseborrhea and hyperplasia of sebaceous glands as well as disturbances in skin microbiome.
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Journal of Physical Organic Chemistry, 2013
pH is one of the few chemical quantities known also to the lay public. However, when we use acid solution more concentrated than 1 M, very few chemists are aware of how to define the activity of the proton under such conditions. In this review, we will describe the scientific efforts to understand in a comprehensible way the behavior of organic ...
Gianfranco Scorrano +1 more
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pH is one of the few chemical quantities known also to the lay public. However, when we use acid solution more concentrated than 1 M, very few chemists are aware of how to define the activity of the proton under such conditions. In this review, we will describe the scientific efforts to understand in a comprehensible way the behavior of organic ...
Gianfranco Scorrano +1 more
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An algorithm for Ph/Ph/c queues
European Journal of Operational Research, 1986Abstract In this paper a new algorithm is presented for the numerical analysis of multi-server queueing systems with interarrival and service time distributions of phase type, including both finite and infinite capacity models. The algorithm is based on the iterative solution of balance equations by using successive overrelaxation and aggregation ...
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pH and Level Controller for a pH Neutralization Process
Industrial & Engineering Chemistry Research, 2001A model reference adaptive control scheme is designed for the control of both the pH and level variables in a neutralization process in a continuously stirred tank reactor. In this adaptive scheme, the control and parameter estimation laws are derived based on a reference model approach for nonlinearly parametrized systems.
Loh, A.-P., De, D.S., Krishnaswamy, P.R.
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International pH scales and certification of pH
Analytical Chemistry, 1991Arne Salomon +2 more
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The Physics of pH and Surface pH Measurement
1992The importance of hydrogen ion activity in biological systems is well known. Significantly, Sorensen’s pioneering treatise [11] on the definition and determination of hydrogen ion activity had the title “Enzyme Studies.”
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