Results 31 to 40 of about 4,058,445 (286)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The Ph Paradox

Science of The Total Environment
This paper highlights the critical role of pH or proton activity measurements in environmental studies and emphasises the importance of applying proper statistical approaches when handling pH data. This allows for more informed decisions to effectively manage environmental data such as from mining influenced water.
Kagiso Samuel More, Christian Wolkersdorfer   +1 more
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The pH of the skin surface and its impact on the barrier function [PDF]

, 2006
The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Korting, Hans Christian, Schmid-Wendtner, M.-H.   +1 more
core   +1 more source

Kulturelle Passung zwischen Familie und Schule im Kontext von Transitionen im Schuleingangsbereich – Erkenntnisse aus einer qualitativ-ethnografischen Längsschnittstudie über sozial privilegierte Familien

Schweizerische Zeitschrift für Bildungswissenschaften
Im vorliegenden Beitrag werden Erkenntnisse zur kulturellen Passung zwischen sozial privilegierten Familien und der Schule präsentiert. Sie resultieren aus einer qualitativ-ethnografischen Längsschnittstudie, die im Kanton Bern durchgeführt wurde.
Doris Edelmann, Claudia Schletti, Kathrin Beeler   +2 more
doaj   +1 more source

The Study and Comparison of Family Performance and Psychological Profile of Students in Martyred Families with Remarried and Non–remarried Mothers. [PDF]

فصلنامه نوآوری‌های آموزشی, 2005
Three–hundred and seventy–three male and female students from martyred families attending high schools for martyred families were selected by using cluster sampling in four provinces of Tehran, Kermanshah, Ardebil and Chahar Mahal and Bakhtiari.
Hadi Keramati, Alireza Moradi, Manizhe Kaveh   +2 more
doaj  

MODELING OF THE OPTIMAL STRUCTURE OF MEAT PROCESSING ENTERPRISES

Фінансово-кредитна діяльність: проблеми теорії та практики, 2021
In today’s economic conditions, problems of functioning of domestic enterprises are not limited by lack of sources of financing of assets, but also often associated with inefficient investment in specific components of property, which adversely affects ...
N. O. Kovalchuk, M. G. Marych, L. V. Popova, A. O. Viknianska   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Markkinointiviestinnän kehittäminen – Case PH-Center [PDF]

, 2021
Opinnäytetyön tarkoituksena oli tutkia ja kehittää PH-Centerin markkinointiviestintää. Ensimmäisenä tavoitteena oli toteuttaa PH-Centerin markkinointiviestintään liittyvä kvantitatiivinen tutkimus nykyisille ja potentiaalisille uusille asiakkaille ...
Hellinen, Riikka
core