Results 31 to 40 of about 2,554,487 (249)

Kalkulierte Ambivalenz im digitalen Raum

open access: yesMedienimpulse
Der Beitrag untersucht die strategische Normalisierung rechtsextremer Narrative im digitalen Raum am Beispiel von Dogwhistling, Meme-Kultur und codierter Symbolik.
Christian Leutgeb   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Ästhetische Überlegungen zur Medienpädagogik

open access: yesMedienimpulse
Das ästhetische Empfinden bei Begegnungen mit Artefakten ist die Essenz jeder näheren Auseinandersetzung mit Kunst, Wissenschaft und Alltagskultur und somit ein wichtiger Parameter für Lernprozesse.
Elke Hackl, Alexandra Scharl, Jelena Ojo
doaj   +1 more source

Scalable Game Design Switzerland

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung, 2018
Das Modul «Medien und Informatik» des Lehrplans 21 verlangt von Primarlehrpersonen, dass sie mit ihren Schülerinnen und Schülern verschiedene Kompetenzen und Inhalte im Bereich der Informatik erarbeiten.
Alexander Repenning   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Algorithmisch verstärkte Affekte in 60 Sekunden?

open access: yesMedienimpulse
Der Beitrag analysiert Beispiele für affektive Kommunikationsstrategien in Kurzvideoformaten auf Social-Media-Plattformen wie Instagram und TikTok.
Christian Leutgeb   +2 more
doaj   +1 more source

Fachspezifische Qualitätsprofile von Rechtschreibunterricht in Deutschland und der Schweiz

open access: yesSchweizerische Zeitschrift für Bildungswissenschaften, 2023
Im Rahmen der ländervergleichenden Studie „Professionelle Kompetenzen und Unterrichtshandeln von Primarlehrpersonen im Lernbereich Rechtschreibung“ wurden 43 Rechtschreiblektionen zur Doppelkonsonantenschreibung in den Klassen 3 bis 6 videografiert und ...
Maja Wiprächtiger   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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