Results 51 to 60 of about 3,645,606 (296)

Fachspezifische Qualitätsprofile von Rechtschreibunterricht in Deutschland und der Schweiz

open access: yesSchweizerische Zeitschrift für Bildungswissenschaften, 2023
Im Rahmen der ländervergleichenden Studie „Professionelle Kompetenzen und Unterrichtshandeln von Primarlehrpersonen im Lernbereich Rechtschreibung“ wurden 43 Rechtschreiblektionen zur Doppelkonsonantenschreibung in den Klassen 3 bis 6 videografiert und ...
Maja Wiprächtiger   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Electrochemical microsensors for cutaneous surface analysis: Application to the determination of pH and the antioxidant properties of stratum corneum [PDF]

open access: yes, 2008
Potentiometry and cyclic voltammetry were proposed as simple, reliable and non invasive methods for the simultaneous determination of pH and antioxidant properties of skin.
Ruffien-Ciszak, A   +9 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Molecular analysis of Solanum lycopersicum L. responses to alkaline pH environments

open access: yes, 2023
reservedIl pH del suolo è uno dei fattori principali che condizionano la salute delle piante coltivate in quanto da esso dipende la biodisponibilità di elementi. Valori di pH molto alti o molto bassi possono causare una riduzione delle rese.
PEZZOLI, ASIA
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Praktiken der Differenzbearbeitung im Fachunterricht einer integrativen Schule der Sekundarstufe. Zur Überlagerung von Schulleistung, Peerkultur und Geschlecht

open access: yesGender, 2015
Der Beitrag geht der Frage nach, wie im Deutsch- und Mathematikunterricht einer integrativen achten Klasse einer nicht-gymnasialen Schulform Leistung konstruiert und von peerkulturellen, geschlechtsbezogenen Formen überlagert wird.
Tanja Sturm, Monika Wagner-Willi
doaj   +1 more source

Die ersten 1000: Computational Thinking als obligatorische Ausbildung für Primarschullehrpersonen in der Schweiz

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung, 2020
Die Umsetzung des Lehrplans 21, der mit dem Modul «Medien und Informatik» informatische Bildung (IB) in die Schweizer Primarschulen bringen wird, wirft wichtige Fragen auf: Insbesondere fragt sich, wie die Umsetzung gegen die bei vielen ...
Alexander Repenning   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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