Results 51 to 60 of about 2,554,487 (249)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Editorial 04/2024: Digitalität, Produktion, Verantwortung
MedienimpulseDigitalisierung und Digitalität haben sich als neue gesamtgesellschaftliche Phänomene etabliert und werden in der (medienpädagogischen) Fachliteratur richtigerweise als solche verhandelt und analysiert.
Alessandro Barberi +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Die Wirksamkeit von Lehrer*innenfortbildung aus der Sicht der Fortbildner*innen
Herausforderung Lehrer*innenbildung, 2020 Dieser Beitrag thematisiert die Wirksamkeit von Lehrer*innenfortbildungen sowie wahrgenommene Erwartungen aus der Perspektive der Fortbildner*innen. Die spärliche Forschungslage zu diesem Thema führte zu der Projektidee, den Fokus der Forschung auf die ...
Isabel Wanitschek +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Designing an educational software of mathematics for elementary school students from the point of view of constructivism and its effectiveness [PDF]
فصلنامه نوآوریهای آموزشی, 2004 This investigation studies the view of constructivism computer-based education. The purpose of this study was to produce mathematics educational software based on constructivism and studies its effectiveness with two randomly chosen groups of subjects ...
Mostafa Sheykhzadeh +1 more
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Schweizerische Zeitschrift für Bildungswissenschaften, 2023 Christelle Hayoz +2 more
doaj +1 more source
IACR Cryptol. ePrint Arch., 2014 The author greatly appreciate suggestions and help of Professor Lew Gordeew and the anonymous reviewers for their comments and ...
openaire +3 more sources
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source