Results 71 to 80 of about 7,458,423 (270)

Designing an educational software of mathematics for elementary school students from the point of view of constructivism and its effectiveness [PDF]

فصلنامه نوآوری‌های آموزشی, 2004
This investigation studies the view of constructivism computer-based education. The purpose of this study was to produce mathematics educational software based on constructivism and studies its effectiveness with two randomly chosen groups of subjects ...
Mostafa Sheykhzadeh, Mahmood Mehrmohammadi   +1 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Education and continuing professional development of physical education teachers – structures, challenges and current research tendencies

Schweizerische Zeitschrift für Bildungswissenschaften, 2023
Christelle Hayoz, Ilaria Ferrari, Matthias Baumgartner   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Determination of F_pi from Distributions of Dirac Operator Eigenvalues with Imaginary Density [PDF]

, 2007
In the epsilon-regime of lattice QCD one can get an accurate measurement of the pion decay constant F_pi by monitoring how just one single Dirac operator eigenvalue splits into two when subjected to two different external vector sources.
Akemann, G, Damgaard, PH
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Kunst und Gestaltung in Verknüpfung mit Medienbildung

Medienimpulse
Das eigenständige und reflexive Gestalten von Medien wird im österreichischen Primarstufencurriculum im Unterrichtsfach Kunst und Gestaltung als eine zentrale Fähigkeit angeführt.
Anastasiya Savran-Wellscheid, Rolf Laven   +1 more
doaj   +1 more source

Results of the Bank’s survey of wage-setting in Belgian firms [PDF]

The analysis presented is the outcome of a survey conducted by the Bank and forming the Belgian component of an initiative launched by the Wage Dynamics Network (WDN), in order to accompany the empirical analysis based on individual employees’ wage data ...
M. Druant, Ph. Delhez, Ph. Du Caju
core  

On smooth surfaces in projective four-space lying on quartic hypersurfaces with isolated singularities

, 1999
We prove that a smooth surface, non of general type, in projective four-space, which lies on a quartic hypersurface with isolated singularities has degree at most 27 (in fact we prove a slightly more general result)
Ellia, Ph., Franco, D.
core   +1 more source