Results 71 to 80 of about 3,645,606 (296)

Editorial 04/2024: Digitalität, Produktion, Verantwortung

open access: yesMedienimpulse
Digitalisierung und Digitalität haben sich als neue gesamtgesellschaftliche Phänomene etabliert und werden in der (medienpädagogischen) Fachliteratur richtigerweise als solche verhandelt und analysiert.
Alessandro Barberi   +3 more
doaj   +1 more source

Die Wirksamkeit von Lehrer*innenfortbildung aus der Sicht der Fortbildner*innen

open access: yesHerausforderung Lehrer*innenbildung, 2020
Dieser Beitrag thematisiert die Wirksamkeit von Lehrer*innenfortbildungen sowie wahrgenommene Erwartungen aus der Perspektive der Fortbildner*innen. Die spärliche Forschungslage zu diesem Thema führte zu der Projektidee, den Fokus der Forschung auf die ...
Isabel Wanitschek   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Vrednosti pH mešavina fungicida, insekticida i kompleksnih đubriva, zavisno od kvaliteta vode [PDF]

open access: yes, 2015
The paper deals with the effect of water quality on the pH value of fungicides, insecticides, mineral fertilizers and their mixtures. The fungicides propineb (Antracol WP-70) and mancozeb (Dithane M-70), insecticides pirimiphos-methyl (Actellic-50) and
Vukovic, Slavica   +3 more
core  

Designing an educational software of mathematics for elementary school students from the point of view of constructivism and its effectiveness [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2004
This investigation studies the view of constructivism computer-based education. The purpose of this study was to produce mathematics educational software based on constructivism and studies its effectiveness with two randomly chosen groups of subjects ...
Mostafa Sheykhzadeh   +1 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Education and continuing professional development of physical education teachers – structures, challenges and current research tendencies

open access: yesSchweizerische Zeitschrift für Bildungswissenschaften, 2023
Christelle Hayoz   +2 more
doaj   +1 more source

PH = PSPACE

open access: yesIACR Cryptol. ePrint Arch., 2014
The author greatly appreciate suggestions and help of Professor Lew Gordeew and the anonymous reviewers for their comments and ...
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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