Results 151 to 160 of about 531,900 (348)

Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

Medicinal research reviews (Print), 2019
Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to understand phage pharmacokinetics in animals and humans, investigating bacteriophages as therapeutics, nanocarriers or microbiome components.
K. Dąbrowska
semanticscholar   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Correction: Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2

Virology Journal, 2023
Mohamed S. Fayez, Toka A. Hakim, Bishoy Maher Zaki, Salsabil Makky, Mohamed Abdelmoteleb, Kareem Essam, Anan Safwat, Abdallah S. Abdelsattar, Ayman El-Shibiny   +8 more
doaj   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Specific immunoassays confirm association of Mycobacterium avium subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus [PDF]

, 2009
Background Mycobacterium avium subspecies paratuberculosis (MAP) is a versatile pathogen with a broad host range. Its association with type-1 diabetes mellitus (T1DM) has been recently proposed.
Ahmed, Niyaz, Fadda, Giovanni, Gerlach, Gerald, Hasnain, Seyed E., Paccagnini, Daniela, Rosu, Valentina, Sechi, Leonardo Antonio, Zanetti, Stefania Anna Lucia   +7 more
core  

Editorial: Standards in personalized phage therapy: from phage collection to phage production

Frontiers in Cellular and Infection Microbiology
Non peer ...
Kiljunen, S., Resch, G.
openaire   +5 more sources

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Efficacy of systemic temozolomide‐activated phage‐targeted gene therapy in human glioblastoma

EMBO Molecular Medicine, 2019
Glioblastoma multiforme (GBM) is the most lethal primary intracranial malignant neoplasm in adults and most resistant to treatment. Integration of gene therapy and chemotherapy, chemovirotherapy, has the potential to improve treatment. We have introduced
Justyna Magdalena Przystal, Sajee Waramit, Md Zahidul Islam Pranjol, Wenqing Yan, Grace Chu, Aitthiphon Chongchai, Gargi Samarth, Nagore Gene Olaciregui, Ghazaleh Tabatabai, Angel Montero Carcaboso, Eric Ofori Aboagye, Keittisak Suwan, Amin Hajitou   +12 more
doaj   +1 more source

Bacteriophages as a model for studying carbon regulation in aquatic system [PDF]

, 2012
The interconversion of carbon in organic, inorganic and refractory carbon is still beyond the grasp of present environmentalists. The bacteria and their phages, being the most abundant constituents of the aquatic environment, represent an ideal model for
Sandhya Swaminathan, Satish K. Lokhande, Swapnil G. Sanmukh, Waman N. Paunikar   +3 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source