Results 181 to 190 of about 531,900 (348)

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing   +4 more
wiley   +1 more source

Characterization and therapeutic potential of phage vB_Eco_ZCEC08 against multidrug-resistant uropathogenic Escherichia coli

open access: yesBMC Microbiology
Background Urinary tract infections (UTIs) caused by antibiotic-resistant bacteria have become a significant public health concern. The increasing ineffectiveness of antibiotics has led to a renewed focus on investigating other strategies, such as ...
Assmaa H. Hussein   +4 more
doaj   +1 more source

Phage–host coevolution in natural populations

open access: yesNature Microbiology, 2022
Damien Piel   +19 more
semanticscholar   +1 more source

Digital Point‐of‐Care Testing Device Based on Bioluminescent Pyrophosphate in Real‐Time and Recombinase‐aid Amplification

open access: yesAdvanced Intelligent Systems, EarlyView.
A point‐of‐care testing method based on solvent‐responsive magnetic beads suitable for large‐area diagnosis and mutation screening in remote areas was developed to detect it by combining bioluminescenct pyrophosphate in real‐time technology and recombinase‐aid amplification technology.
Zhongjie Fei   +8 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Dynamischer Austausch von Bindemolekülen steigert die Effizienz der Proteinmarkierung in DNA‐PAINT um das bis zu 15‐Fache

open access: yesAngewandte Chemie, EarlyView.
Der dynamische Austausch von Bindemolekülen (Dynamic Binder Exchange; DyBE) nutzt transiente Binde–Zielprotein‐Interaktionen, um die Markierungseffizienz in der superauflösenden Mikroskopie um das 15‐Fache zu steigern. DyBE kartiert die Organisation von Rezeptor‐Tyrosinkinasen (RTKs), einschließlich HER2‐Homodimere und EGFR–HER2‐Heterodimere, auf der ...
Clemens Steinek   +5 more
wiley   +1 more source

Dynamic Binder Exchange Improves Protein Labeling Efficiency in DNA‐PAINT up to 15‐Fold

open access: yesAngewandte Chemie International Edition, EarlyView.
Dynamic Binder Exchange (DyBE) leverages transient binder–target interactions to enhance labeling efficiency by up to 15‐fold in super‐resolution microscopy. DyBE maps nanoscale receptor tyrosine kinase (RTK) assemblies, including HER2 homodimers and EGFR–HER2 heterodimers, advancing single‐protein spatial proteomics.
Clemens Steinek   +5 more
wiley   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

open access: yesAnalysis &Sensing, EarlyView.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro   +7 more
wiley   +1 more source

Surfactant‐Enhanced Electrospun Nanofiber Filters for Efficient Viral and Bacterial Inactivation

open access: yesJournal of Applied Polymer Science, EarlyView.
In this work, electrospun polyacrylonitrile (PAN) nanofibrous filters functionalized with surfactants (CTAB, CPC, and SDS) were developed for air filtration applications. The PAN nanofiber mats enable efficient particulate matter capture while simultaneously providing antimicrobial and antiviral activity against bacteria (E. coli and S.
Edilton N. da Silva   +9 more
wiley   +1 more source

PHAGE Impact and the Impact of Phages

open access: yesPHAGE, 2023
Martha, Clokie   +1 more
openaire   +2 more sources

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