Results 201 to 210 of about 359,710 (297)

The Gut–Brain Axis in Parkinson's Disease: From Clinical Observation toward Mechanism‐Based Precision Medicine

Movement Disorders, EarlyView.
Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans, Per Borghammer, Ronald F. Pfeiffer, Silke Appel‐Cresswell, Ali Keshavarzian   +4 more
wiley   +1 more source

An Integrated System for Geobacillus Protoplast Formation, Transfection, Recombinant Genomes Rebooting, Efficient Propagation, and Genomic DNA Isolation of the Thermophilic Bacteriophage TP-84. [PDF]

Microbiologyopen
Sobolewski I, Adamowicz K, Chodorski J, Skowron PM, Zylicz-Stachula A.   +4 more
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Substrate morphology modulates bacteriophage mobility and alters bactericidal potency. [PDF]

PLoS One
Wang H, Awolusi OO, Jaganathan SK, Lyu J, Liu C, Tucker N, Onarinde BA.   +6 more
europepmc   +1 more source

Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance

Medicine Advances, EarlyView.
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani, Shangavy Pandiarajan, Kunal Biswas, Manickam Rajkumar, Agnishwar Girigoswami, Koyeli Girigoswami   +5 more
wiley   +1 more source

Beyond Antibiotics: Bacteriophage Therapy Against Multidrug-Resistant Pathogens in the Era of Antimicrobial Resistance. [PDF]

Cureus
Avanigadda BV, Venigalla RK, Ede R, Jetti PR, Kandi V, Suvvari TK.   +5 more
europepmc   +1 more source

Rethinking the tumor microbiome: Methodological challenges and a framework for rigorous research

mLife, EarlyView.
Abstract The intratumoral microbiome, as an essential component of the tumor microenvironment, has attracted increasing attention in recent years. The tumor microbiota displays an intricate interplay with its biological behaviors. However, emerging controversies, including the retraction of Poore et al.'s article, highlight significant challenges ...
Lingxuan Zhu, Zhixing Deng, Weiming Mou, Gengwen Deng, Hongyu Lu, Liling Xu, Shujia Lin, Hongsen Huang, Keren Wu, Qiheng Liang, Hao Li, Ziwen Zheng, Anqi Lin, Peng Luo   +13 more
wiley   +1 more source

The near-complete genome sequence of vB_AgrS_573, a lytic <i>Agrobacterium tumefaciens</i> phage isolated from karst cave sediment. [PDF]

Microbiol Resour Announc
Wu Q, Li Z, Yang Y, Fang Z, Xiang L, Weng Q.   +5 more
europepmc   +1 more source