Results 201 to 210 of about 327,788 (316)

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Mycobacterium intracellulare M.i.198—A Promising Strain for Studying Pathogenesis of Nontuberculous Mycobacterial Pulmonary Disease (NTM‐PD)

Microbiology and Immunology, EarlyView.
ABSTRACT In this review, we introduce a promising strain for studying pathogenesis of nontuberculous mycobacterial pulmonary disease (NTM‐PD), Mycobacterium intracellulare M.i.198. M.i.198 was isolated from a patient with progressive Mycobacterium avium‐intracellulare complex pulmonary disease (MAC‐PD) in whom surgical operation was required to ...
Yoshitaka Tateishi, Ryoji Maekura, Yukiko Nishiuchi, Sohkichi Matsumoto   +3 more
wiley   +1 more source

Isolation and characterization of a broad-spectrum <i>Salmonella</i> phage targeting featural foodborne serotypes. [PDF]

Front Microbiol
Zhang L, Zhong C, Yang M, Shu M, Zhang JH, Li J, Wu GP.   +6 more
europepmc   +1 more source

Genome Analysis of Corynebacterium ulcerans Isolates Chronologically Recovered From the Same Cat for Two Years: Circulation in a Cat Shelter

Microbiology and Immunology, EarlyView.
ABSTRACT Toxigenic Corynebacterium ulcerans, a zoonotic pathogen, was isolated repeatedly from a cat in an in‐house group in Japan. Although the cat was cured once by antibiotic treatment, clonal isolates of the original pathogenic strain were recovered repeatedly during a 2‐year course.
Ryoko Jikihara, Miyuki Kimura, Hyun Kim, Tsuyoshi Sekizuka, Masatomo Morita, Makoto Kuroda, Akihiko Yamamoto, Mitsutoshi Senoh, Masaaki Iwaki   +8 more
wiley   +1 more source

When bacteriophages encounter macrophages during their journey through the human body. [PDF]

Front Cell Infect Microbiol
Cieślik M, Gębicka M, Wójcicki M, Górski A, Jończyk-Matysiak E.   +4 more
europepmc   +1 more source

Hotter, faster, sicker? Warming shifts the cost of infection from individuals to populations

Journal of Animal Ecology, EarlyView.
This study examines how temperature alters disease impacts across biological scales in a host–pathogen system. We found infected hosts appear healthiest at warm temperatures, yet populations suffer most. This suggests climate warming may intensify disease impacts for populations in ways traditional individual‐level virulence metrics fail to predict ...
Nathan J. Butterworth, Kerri J. Moore, Matthew D. Hall   +2 more
wiley   +1 more source

DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity. [PDF]

Proc Natl Acad Sci U S A
Ernst L, Gätgens C, Rackow B, Pozhydaieva N, Gaaloul E, Krüger A, Seiffarth J, Bund M, Joisten-Rosenthal V, Kohlheyer D, Usadel B, Harms A, Höfer K, Frunzke J.   +13 more
europepmc   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

Australian Endodontic Journal, EarlyView.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima, Analia Gabriella Borges Ferraz Facury   +1 more
wiley   +1 more source

Dissecting the disconnect between circuit activation and dominant adaptive evolution in cytoplasmic phage-assisted continuous evolution (PACE) of an EGFR nanobody. [PDF]

Front Bioeng Biotechnol
Chuang JN, Purcell J, Sangalli L, Rosenbluh J, Knott GJ, Corrie S, Garnier G.   +6 more
europepmc   +1 more source

Isolation of novel phages from a resistant Dorea longicatena strain reveals genes associated with phage resistance. [PDF]

Npj Viruses
Wang W, Li Z, Gondowardojo GR, Tan L, Wu C, Liu R, Xiao M, Liu C.   +7 more
europepmc   +1 more source