Phages from Genus Bruynoghevirus and Phage Therapy: Pseudomonas Phage Delta Case [PDF]
Viruses, 2021 The applicability and safety of bacteriophage Delta as a potential anti-Pseudomonas aeruginosa agent belonging to genus Bruynoghevirus (family Podoviridae) was characterised. Phage Delta belongs to the species Pseudomonas virus PaP3, which has been described as a temperate, with cos sites at the end of the genome.
Petar Knezevic +5 more
openaire +4 more sources
Microorganisms, 2022 Treatment of infections caused by bacteria has become more complex due to the increasing number of bacterial strains that are resistant to conventional antimicrobial therapy. A highly promising alternative appears to be bacteriophage (phage) therapy, in which natural predators of bacteria, bacteriophages, play a role.
Marek Straka +2 more
openaire +3 more sources
Adapting a Phage to Combat Phage Resistance [PDF]
Antibiotics, 2020 Phage therapy is becoming a widely recognized alternative for fighting pathogenic bacteria due to increasing antibiotic resistance problems. However, one of the common concerns related to the use of phages is the evolution of bacterial resistance against the phages, putatively disabling the treatment.
Mäkelä, Kati +5 more
openaire +6 more sources
Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. [PDF]
, 2014 Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation.
He, Xuesong +13 more
core +1 more source
Characterization of newly isolated lytic bacteriophages active against Acinetobacter baumannii [PDF]
, 2014 Based on genotyping and host range, two newly isolated lytic bacteriophages, myovirus vB_AbaM_Acibel004 and podovirus vB_AbaP_Acibel007, active against Acinetobacter baumannii clinical strains, were selected from a new phage library for further ...
De Vos, Daniel +9 more
core +17 more sources
Results in Chemistry, 2023 Contamination with bacteria and organic matters is becoming a serious challenge for governments and a central issue for public health. Biosynthesized silver nanoparticles (AgNPs) are currently gaining attention due to the additional properties provided ...
Salsabil Makky +10 more
doaj +1 more source
Anti-phage islands force their target phage to directly mediate island excision and spread. [PDF]
, 2018 Vibrio cholerae, the causative agent of the diarrheal disease cholera, is antagonized by the lytic phage ICP1 in the aquatic environment and in human hosts. Mobile genetic elements called PLEs (phage-inducible chromosomal island-like elements) protect V.
McKitterick, Amelia C, Seed, Kimberley D
core +1 more source
Antibacterial Efficacy of Two Commercially Available Bacteriophage Formulations, Staphylococcal Bacteriophage and PYO Bacteriophage, Against Methicillin-Resistant Staphylococcus aureus: Prevention and Eradication of Biofilm Formation and Control of a Systemic Infection of Galleria mellonella Larvae [PDF]
, 2020 Sessile bacteria growing on surfaces are more resistant to standard antibiotics than their planktonic counterpart. Due to their antimicrobial properties, bacteriophages have re-emerged as a promising approach to treat bacterial biofilm-associated ...
Di Luca, Mariagrazia +4 more
core +1 more source
Systematic analysis of putative phage-phage interactions on minimum-sized phage cocktails [PDF]
Scientific Reports, 2022 AbstractThe application of bacteriophages as antibacterial agents has many benefits in the “post-antibiotic age”. To increase the number of successfully targeted bacterial strains, phage cocktails, instead of a single phage, are commonly formulated. Nevertheless, there is currently no consensus pipeline for phage cocktail development.
Molina, Felipe +4 more
openaire +4 more sources
Two Newly Isolated Enterobacter-Specific Bacteriophages: Biological Properties and Stability Studies
Viruses, 2022 In an era of antibiotic therapy crisis caused by spreading antimicrobial resistance, and when recurrent urinary tract infections constitute a serious social and medical problem, the isolation and complex characterization of phages with a potential ...
Martyna Cieślik +5 more
doaj +1 more source