Results 31 to 40 of about 327,788 (316)

Phage Cocktails and the Future of Phage Therapy

open access: yesFuture Microbiology, 2013
Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade.
Benjamin K, Chan   +2 more
openaire   +2 more sources

Characterization of the biosynthesized Syzygium aromaticum-mediated silver nanoparticles and its antibacterial and antibiofilm activity in combination with bacteriophage

open access: yesResults in Chemistry, 2023
Contamination with bacteria and organic matters is becoming a serious challenge for governments and a central issue for public health. Biosynthesized silver nanoparticles (AgNPs) are currently gaining attention due to the additional properties provided ...
Salsabil Makky   +10 more
doaj   +1 more source

Mucosal Environment Induces Phage Susceptibility in Streptococcus mutans [PDF]

open access: yes, 2022
Pathogenic bacteria are attracted toward mucosa, as it is their way of entry into the body. However, we know surprisingly little about the phage-bacterium interactions in the mucosal environment. Here, we explored the effect of the mucosal environment on
Sundberg, Lotta-Riina   +2 more
core   +1 more source

The Lytic Activity of Bacteriophage ZCSE9 against Salmonella enterica and Its Synergistic Effects with Kanamycin

open access: yesViruses, 2023
Salmonella, the causative agent of several diseases in humans and animals, including salmonellosis, septicemia, typhoid fever, and fowl typhoid, poses a serious threat to global public health and food safety. Globally, reports of therapeutic failures are
Abdallah S. Abdelsattar   +7 more
doaj   +1 more source

Repressor of Phage 16-3 with Altered Binding Specificity Indicates Spatial Differences in Repressor-Operator Complexes [PDF]

open access: yes, 2006
The C repressor protein of phage 16-3, which is required for establishing and maintaining lysogeny, recognizes structurally different operators which differ by 2 bp in the length of the spacer between the conserved palindromic sequences.
Papp, P. Péter   +2 more
core   +1 more source

First‐in‐human application of double‐stranded RNA bacteriophage in the treatment of pulmonary Pseudomonas aeruginosa infection

open access: yesMicrobial Biotechnology, 2023
A double‐stranded RNA (dsRNA) phage phiYY is able to kill a pyomelanin‐producing Pseudomonas aeruginosa strain, which was isolated from a 40‐year‐old man with interstitial lung disease (ILD) and chronic lung infection.
Linlin Li   +12 more
doaj   +1 more source

Phascinating Phages

open access: yesMicroorganisms, 2022
Treatment of infections caused by bacteria has become more complex due to the increasing number of bacterial strains that are resistant to conventional antimicrobial therapy. A highly promising alternative appears to be bacteriophage (phage) therapy, in which natural predators of bacteria, bacteriophages, play a role.
Marek Straka   +2 more
openaire   +3 more sources

Phage-like protein translocation structures. [PDF]

open access: yes, 2022
(A) PLTS gene clusters in ANME genomes. (B) Alignment of PAAR domain spike proteins. PAAR motifs highlighted in blue. Alignments were made using muscle 3.8.31 with default settings, and alignment file can be found in S1 Data.
Danielle Goudeau (8455311)   +16 more
core   +1 more source

Endolysin Regulation in Phage Mu Lysis

open access: yesmBio, 2022
Bacteriophage Mu is a paradigm coliphage studied mainly because of its use of transposition for genome replication. However, in extensive nonsense mutant screens, only one lysis gene has been identified, the endolysin gp22.
Jake S. Chamblee   +7 more
doaj   +1 more source

New Insights into the Structure and Assembly of Bacteriophage P1

open access: yesViruses, 2022
Bacteriophage P1 is the premier transducing phage of E. coli. Despite its prominence in advancing E. coli genetics, modern molecular techniques have not been applied to thoroughly understand P1 structure.
Miguel F. Gonzales   +6 more
doaj   +1 more source

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