Results 11 to 20 of about 353,959 (297)

Isolation and characterisation of Klebsiella phages for phage therapy [PDF]

PHAGE: Therapy, Applications, and Research, 2020
Abstract Klebsiella is a clinically important pathogen causing a variety of antimicrobial resistant infections in both community and nosocomial settings, particularly pneumonia, urinary tract infection and sepsis. Bacteriophage (phage) therapy is being considered as a primary option for the treatment
Eleanor Townsend, Lucy Kelly, Lucy Gannon, George Muscatt, Rhys Dunstan, Slawomir Michniewski, Hari Sapkota, Saija J Kiljunen, Anna Kolsi, Mikael Skurnik, Trevor Lithgow, Andrew D. Millard, Eleanor Jameson   +12 more
openaire   +6 more sources

Adapting a Phage to Combat Phage Resistance [PDF]

Antibiotics, 2020
Phage therapy is becoming a widely recognized alternative for fighting pathogenic bacteria due to increasing antibiotic resistance problems. However, one of the common concerns related to the use of phages is the evolution of bacterial resistance against the phages, putatively disabling the treatment.
Mäkelä, Kati, Hoikkala, Ville, Ravantti, Janne J., Sundberg, Lotta-Riina, Laanto, Elina   +5 more
openaire   +6 more sources

Case Report: Chronic Bacterial Prostatitis Treated With Phage Therapy After Multiple Failed Antibiotic Treatments

Frontiers in Pharmacology, 2021
Background: Chronic Bacterial Prostatitis (CBP) is an inflammatory condition caused by a persistent bacterial infection of the prostate gland and its surrounding areas in the male pelvic region. It is most common in men under 50 years of age.
Apurva Virmani Johri, Pranav Johri, Naomi Hoyle, Levan Pipia, Lia Nadareishvili, Dea Nizharadze   +5 more
doaj   +1 more source

Genetic basis of phage-host interaction: Towards effective phage therapy of non-typhoidal Salmonella

, 2022
Non-typhoidal Salmonella (NTS) have adapted to cause invasive illness in humans. Bacteria have developed MDR against current antibiotics. Bacteriophage therapy is the hope for bacterial treatment however one of the key limitations is the limited host ...
Mohammed, M.
core   +4 more sources

Case report: Successful treatment of recurrent E. coli infection with bacteriophage therapy for patient suffering from chronic bacterial prostatitis

Frontiers in Pharmacology, 2023
Background: Chronic Bacterial Prostatitis (CBP) is inflammation of the prostate caused by bacterial infection. An estimated 8.2% of men have prostatitis, most commonly under the age of 50.
Apurva Virmani Johri, Pranav Johri, Naomi Hoyle, Naomi Hoyle, Lia Nadareishvili, Levan Pipia, Dea Nizharadze   +6 more
doaj   +1 more source

Isolation and identification of the broad-spectrum high-efficiency phage vB_SalP_LDW16 and its therapeutic application in chickens

BMC Veterinary Research, 2022
Background Salmonella infection in livestock and poultry causes salmonellosis, and is mainly treated using antibiotics. However, the misuse use of antibiotics often triggers the emergence of multi-drug-resistant Salmonella strains.
Shengliang Cao, Wenwen Yang, Xihui Zhu, Cheng Liu, Jianbiao Lu, Zhenshu Si, Lanying Pei, Leilei Zhang, Wensi Hu, Yanlan Li, Zhiwei Wang, Zheyu Pang, Xijuan Xue, Yubao Li   +13 more
doaj   +1 more source

DNA Dye Sytox Green in Detection of Bacteriolytic Activity: High Speed, Precision and Sensitivity Demonstrated With Endolysins

Frontiers in Microbiology, 2021
Introduction: Increasing number of deaths from multi-drug resistant bacterial infections has caused both the World Health Organization and the Centers for Disease Control and Prevention to repeatedly call for development of new, non-traditional ...
Marek Harhala, Marek Harhala, Katarzyna Gembara, Katarzyna Gembara, Paulina Miernikiewicz, Barbara Owczarek, Zuzanna Kaźmierczak, Zuzanna Kaźmierczak, Joanna Majewska, Daniel C. Nelson, Krystyna Dąbrowska, Krystyna Dąbrowska   +11 more
doaj   +1 more source

Immunogenicity of Endolysin PlyC

Antibiotics, 2022
Endolysins are bacteriolytic enzymes derived from bacteriophages. They represent an alternative to antibiotics, since they are not susceptible to conventional antimicrobial resistance mechanisms.
Marek Adam Harhala, Katarzyna Gembara, Daniel C. Nelson, Paulina Miernikiewicz, Krystyna Dąbrowska   +4 more
doaj   +1 more source

Phages and Immunomodulation [PDF]

Future Microbiology, 2017
In the past years, the microbiome and its role in the pathophysiology of diseases have gained great interest. The progress of our knowledge in this field opens completely novel prospects for treating disorders, including those which are most challenging to medicine today.
Andrzej Górski, Dąbrowska, Krystyna, Ryszard Andrzej Międzybrodzki, Weber-Dąbrowska, Beata, Łusiak-Szelachowska, Marzanna, Jończyk-Matysiak, Ewa, Jan Jakub Borysowski   +6 more
openaire   +2 more sources

Phage-induced diversification improves host evolvability. [PDF]

, 2013
Bacteriophage (viruses that infect bacteria) are of key importance in ecological processes at scales from biofilms to biogeochemical cycles. Close interaction can lead to antagonistic coevolution of phage and their hosts.
HT Williams (21828014)
core   +6 more sources