iNew Medicine, EarlyView.This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li +4 more
wiley +1 more source
A fully synthetic Golden Gate assembly system for engineering a <i>Pseudomonas aeruginosa</i> phiKMV-like phage. [PDF]
Proc Natl Acad Sci U S ASikkema AP +13 more
europepmc +1 more source
Therapeutic Gene Editing: DNA Repair Pathways, Emerging Editors, and Clinical Progress
iNew Medicine, EarlyView.ABSTRACT The field of gene editing has evolved rapidly over the past decade, progressing from programmable zinc‐finger nucleases (ZFNs) and transcription activator‐like effector nucleases (TALENs) to the widespread adoption of CRISPR‐Cas systems. First‐generation editors catalyzed genome engineering by introducing targeted double‐strand breaks (DSBs ...
Li‐Kuang Tsai +7 more
wiley +1 more source
Bacteriophage vB_SalS_KY05 controls <i>Salmonella</i> in poultry without disrupting cecal microbiota composition. [PDF]
Vet QWu WY, Wang R, An YN, Lin YY.
europepmc +1 more source
iNew Medicine, EarlyView.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
Broth Optical Density-Based Assessment for Phage Therapy: Turbidity Reduction, Antibacterial Virulence, and Time-Kill. [PDF]
VirusesAbedon ST.
europepmc +1 more source
Gut microbiome‐derived metabolites show promise in cancer research and therapy
Interdisciplinary Medicine, EarlyView.The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang +4 more
wiley +1 more source
Novel Lytic Bacteriophage PAT-A: Isolation, Characterization, Genome Analysis, and Biocontrol Potential Against Agrobacterium tumefaciens. [PDF]
MicroorganismsLiang C, Tian W, Liu J, Zhang Z, Li D.
europepmc +1 more source
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy +7 more
wiley +1 more source
Diversity and classification of cyclic-oligonucleotide-based anti-phage signalling systems
Nature Microbiology, 2020 A. Millman +3 more
semanticscholar +1 more source