Results 291 to 300 of about 73,738 (335)
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Phage display antibody libraries: A robust approach for generation of recombinant human monoclonal antibodies.

International Journal of Biological Macromolecules, 2019
Monoclonal antibodies (mAbs) and their derivatives have achieved remarkable success as medicine, targeting both diagnostic and therapeutic applications associated with communicable and non-communicable diseases.
R. Kumar   +4 more
semanticscholar   +1 more source

Phage Peptide Display

2008
Molecular imaging is at the forefront in the advancement of in-vivo diagnosis and monitoring of cancer. New peptide-based molecular probes to facilitate cancer detection are rapidly evolving. Peptide-based molecular probes that target apoptosis, angiogenesis, cell signaling and cell adhesion events are in place. Bacteriophage (phage) display technology,
Jessica, Newton, Susan L, Deutscher
openaire   +2 more sources

Phage display and pharmacogenomics

Pharmacogenomics, 2000
Surface display of genetic diversity is a technology that can produce specific binding agents for almost any target molecule, and is especially well suited for making agents that bind specific proteins. Until now, pharmacogenomic studies have followed the response of cells to drugs and other agents by tracking the mRNAs that encode the proteins of ...
openaire   +2 more sources

Phage Display: An Overview in Context to Drug Discovery.

TIPS - Trends in Pharmacological Sciences, 2019
Peptides are emerging as a new reliable class of therapeutics and, thanks to their lower cost of production, they are becoming established as perfect drug aspirants.
S. Mimmi   +3 more
semanticscholar   +1 more source

Phage Display

Methods in Molecular Biology, 2018
M. Hust, T. S. Lim
semanticscholar   +3 more sources

ANTIBODY PHAGE DISPLAY

Immunology & Cell Biology, 2002
Phage display provides a powerful technique for rapidly selecting a particular binding clone from millions of other irrelevant clones. One of the first applications of this technology was in the display and isolation of monoclonal antibodies. More recently, phage display technology has been increasingly used in other areas of research, such as in the ...
openaire   +3 more sources

The Use of Phage Display in Neurobiology

Current Protocols in Neuroscience, 1995
AbstractPhage display has been extensively used to study protein‐protein interactions, receptor‐ and antibody‐binding sites, and immune responses, to modify protein properties, and to select antibodies against a wide range of different antigens. In the format most often used, a polypeptide is displayed on the surface of a filamentous phage by genetic ...
openaire   +3 more sources

Phase display of proteins

Current Opinion in Biotechnology, 1996
Phage display of proteins continues to be an important technology with a variety of applications. In the past year, advances have been made in coupling rational protein design with the power of the display selection process. In addition to the widely used filamentous phage, other bacteriophage surface expression systems have now been developed, some of
openaire   +5 more sources

Phage Display of RNase A and an Improved Method for Purification of Phages Displaying RNases

Biological Chemistry, 2000
Functional ribonuclease A was presented on the surface of the filamentous phage M13 by fusion to the minor coat protein. RNase activity of the fusion protein was shown by a zymogram assay. In addition, we established a modified method for preparing RNase-displaying phages without contaminating host RNases.
K, Korn, H H, Foerster, U, Hahn
openaire   +2 more sources

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