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Therapeutic Antibodies by Phage Display
Current Pharmaceutical Design, 2017 Antibody phage display is a major technological platform for the generation of fully human antibodies for therapeutic purposes. The in vitro binder selection by phage display allows researchers to have more extensive control over binding parameters and facilitates the isolation of clinical candidate antibodies with desired binding and/or functional ...
H. Shim
semanticscholar +4 more sources
, 2017 Antibody phage display has become an indispensable tool for the discovery and optimization of target-specific monoclonal antibodies suitable for demanding applications including therapeutic reagents. The in vitro nature of the technology enables the rapid and efficient identification of specific binders, as well as greater control over selection ...
심현보
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Advances in antibody phage display technology
Drug Discovery Today, 2022 Phage display technology can be used for the discovery of antibodies for research, diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters that can be optimized when performing phage display selection campaigns ...
Line Ledsgaard +2 more
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Review of phage display: A jack-of-all-trades and master of most biomolecule display.
International Journal of Biological Macromolecules, 2023Phage display was first described by George P. Smith when it was shown that virus particles were capable of presenting foreign proteins on their surface.
Brenda Pei Chui Song +2 more
semanticscholar +1 more source
Recombinant antibodies by phage display for bioanalytical applications.
Biosensors & bioelectronics, 2022Antibody phage display, aimed at preparing antibodies to defined antigens, is a useful replacement for hybridoma technology. The phage system replaces all work stages that follow animal immunization with simple procedures for manipulating DNA and ...
O. Guliy, S. Evstigneeva, L. Dykman
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Phage Display: Simple Evolution in a Petri Dish (Nobel Lecture)
Angewandte Chemie - International Edition, 2019 Playing with evolution: In his Nobel lecture, George P. Smith reconstructs the story of the phage-display idea as he personally experienced it. The development of this technique is a case study in how a scientific advance emerges gradually in incremental
George P Smith
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, 2021
Biosensors have been explored for their excellent potential in the field of biological detection and their application in biomedical diagnosis and have become a rapidly emerging subject.
Ping Xu +5 more
semanticscholar +1 more source
Biosensors have been explored for their excellent potential in the field of biological detection and their application in biomedical diagnosis and have become a rapidly emerging subject.
Ping Xu +5 more
semanticscholar +1 more source
International Journal of Biological Macromolecules, 2022
Antibodies as ideal therapeutic and diagnostic molecules are among the top-selling drugs providing considerable efficacy in disease treatment, especially in cancer therapy.
Seyedeh Zahra Bahojb Mahdavi +8 more
semanticscholar +1 more source
Antibodies as ideal therapeutic and diagnostic molecules are among the top-selling drugs providing considerable efficacy in disease treatment, especially in cancer therapy.
Seyedeh Zahra Bahojb Mahdavi +8 more
semanticscholar +1 more source