Results 81 to 90 of about 73,738 (335)
The fascinating biology behind phage display: filamentous phage assembly
Molecular Microbiology, 2019 With the recently awarded Nobel Prize to the inventor of Phage Display, George Smith, the technique has once more gained attention. However, one should not forget about the biology behind the method.
B. Loh, A. Kuhn, S. Leptihn
semanticscholar +1 more source
Development of antibody technology to identify natural killer cell surface antigens in Xenopus Laevis [PDF]
, 1999 Natural killer (NK)-like lymphocytes have recently been identified in thymectomised (Tx) Xenopus which are capable of spontaneous cytotoxicity towards the MHC- deficient, allogeneic thymus tumour cell line B(_3)B(_7).
Minter, Ralph
core
Advanced Science, EarlyView.When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Generation of hapten-specific recombinant antibodies: antibody phage display technology: a review
Veterinární Medicína, 2005 Production of antibodies has been revolutionized by the development of modern molecular biology methods for the expression of recombinant DNA. Phage display technology represents one of the most powerful tools for production and selection of recombinant ...
J. Brichta, M. Hnilova, T. Viskovic
doaj +1 more source
Expanding the versatility of phage display I: efficient display of peptide-tags on protein VII of the filamentous phage. [PDF]
PLoS ONE, 2011 BACKGROUND: Phage display is a platform for selection of specific binding molecules and this is a clear-cut motivation for increasing its performance.
Geir Åge Løset +2 more
doaj +1 more source
Development and Application of Yeast and Phage Display of Diverse Lanthipeptides
ACS Central Science, 2018 Peptide display has enabled identification and optimization of ligands to many targets. These ligands are usually linear or disulfide-containing peptides that are vulnerable to proteolysis or reduction.
Kenton J. Hetrick +2 more
semanticscholar +1 more source
, 2008 Lipid transfer proteins (LTPs) are the major allergens of Rosaceae fruits in the Mediterranean area. Pru p 3, the LTP and major allergen of peach, is a suitable model for studying food allergy and amino acid sequences related with its IgE-binding ...
Tordesillas Villuendas, Leticia +7 more
core +1 more source
Peptides binding to a Gb3 mimic selected from a phage library [PDF]
, 2004 Peptides binding to a Gb3 mimic were selected from 12mer peptide library. The self-assembled monolayer (SAM) of a Gb3 mimic was formed on the gold surface, and biopanning was carried out with the phage display peptide library.
Sakaki, Akio +11 more
core +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Use of phage display technology to investigate allergen-antibody interactions
, 2000 Phage display is an advanced technology that can be used to characterize the interactions of antibody with antigen at the molecular level. It provides valuable data when applied to the investigation of IgE interaction with allergens.
O'Hehir, R. E. +4 more
core +1 more source