Results 161 to 170 of about 165,430 (355)

Phage Genome Diversity in a Biogas-Producing Microbiome Analyzed by Illumina and Nanopore GridION Sequencing. [PDF]

Microorganisms, 2022
Willenbücher K, Wibberg D, Huang L, Conrady M, Ramm P, Gätcke J, Busche T, Brandt C, Szewzyk U, Schlüter A, Barrero Canosa J, Maus I.   +11 more
europepmc   +1 more source

Deletion mutants of bacteriophage phiX174 [PDF]

, 1972
Mutants of bacteriophage phiX174 have been isolated that are less dense than wild-type phiX particles in CsCl. When mutant viral (+) strand DNA and wild-type complementary (-) strand DNA are hybridized, the resulting duplex molecules have single-stranded
Benbow, Robert M., Sinsheimer, Robert L., Zuccarelli, Anthony J.   +2 more
core  

Identification of four loci isolated from two Streptococcus thermophilus phage genomes responsible for mediating bacteriophage resistance [PDF]

, 2000
Eva Stanley
openalex   +1 more source

The microbiome in cancer

iMeta, EarlyView.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

Strategies for Bacteriophage T5 Mutagenesis: Expanding the Toolbox for Phage Genome Engineering. [PDF]

Front Microbiol, 2021
Ramirez-Chamorro L, Boulanger P, Rossier O.   +2 more
europepmc   +1 more source

PSOSP uncovers pervasive SOS‐independent prophages with distinct genomic and host traits in bacterial genomes

iMeta, EarlyView.
Prophages are ubiquitously present in bacterial genomes, significantly influencing host physiological and ecological functions. We present Prophage SOS‐dependency Predictor (PSOSP), a novel bioinformatics tool that predicts prophages induction modes by analyzing the Heterology Index (HI) of LexA protein binding to target DNA, classifying prophages into
Yali Hao, Mujie Zhang, Xinjuan Lei, Chengrui Zhu, Taoliang Zhang, Yanping Zheng, Xiang Xiao, Huahua Jian   +7 more
wiley   +1 more source

The physical mapping of the genome of MS2-induced DNA-containing P23-2 phage and detecting of MS2-specific sequences in this genome [PDF]

, 2001
N. Yu. Miryuta, A. Yu. Miryuta, Т. П. Перерва   +2 more
openalex   +1 more source

Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae

iMeta, EarlyView.
The global emergence of hypervirulent, carbapenem‐resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 genomes across 90 years, we uncover a core evolutionary constraint—virulence and resistance rarely coexist without trade‐offs. Potent carbapenemases (blaKPC,
Yuchen Wu, Fan Pu, Zelin Yan, Yanyan Zhang, Kaichao Chen, Shengkai Li, Yuezhuo Wang, Heyuan Lun, Tingting Qu, Jing Wang, Heng Li, Danxia Gu, Sheng Chen, Ping He, Rong Zhang, Zhemin Zhou   +15 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Genome sequence of a serotype M3 strain of group AStreptococcus: Phage-encoded toxins, the high-virulence phenotype, and clone emergence [PDF]

, 2002
Stephen B. Beres, Gail L. Sylva, Kent Barbian, Benfang Lei, Jessica Hoff, Nicole D. Mammarella, Meng-Yao Liu, James C. Smoot, Stephen F. Porcella, Larye D. Parkins, David Campbell, T. M. F. Smith, John K. McCormick, Donald Y.M. Leung, Patrick M. Schlievert, James M. Musser   +15 more
openalex   +1 more source