ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor +6 more
wiley +1 more source
ABSTRACT Large‐scale double‐digest RAD sequencing (ddRADseq) datasets generated for genotyping are increasingly available in aquaculture, yet their unmapped reads remain largely unexplored for pathogen surveillance. Here, we evaluated the utility and limitations of repurposing unmapped ddRADseq reads to examine pathogen‐associated and disease ...
Nguyen Thanh Vu +11 more
wiley +1 more source
Genomic and biological characterization of three lytic phages targeting <i>Vibrio parahaemolyticus</i> and their application in a raw salmon model. [PDF]
Zhang M, Feng X, Liu P, Qu W, Jin M.
europepmc +1 more source
ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz +5 more
wiley +1 more source
Co-occurrence of <i>Yersinia pestis</i> and a lytic bacteriophage in brain tissue of <i>Eothenomys miletus</i>. [PDF]
Lyu D +17 more
europepmc +1 more source
YdcI, a LysR‐type transcription regulator in Escherichia coli, regulates loci like iraP and mqo. Its expression is induced by (p)ppGpp under stress conditions, and protein levels rise during mid‐exponential growth, connecting its role to stress response and metabolism control. ABSTRACT YdcI, a LysR‐type transcription regulator, has been associated with
Ria Basu Roy, Karin Schnetz
wiley +1 more source
Genomic and functional characterization of <i>six</i> novel phages targeting multidrug<i>-</i>resistant <i>Escherichia coli</i>: prom<i>isi</i>ng candidates for clinical phage therapy. [PDF]
Xiong L +9 more
europepmc +1 more source
A Mobile Glycosylation Locus Modulates Cell Wall Architecture in Lactobacillus crispatus
Serial propagation of Lactobacillus crispatus triggers transposon‐mediated loss of a mobile glycosylation gene fragment (GT3), destabilising the glycosyltransferase complex and remodelling the cell wall with 20%–25% thinner peptidoglycan, while sugar composition remains unchanged.
P. Achterberg +8 more
wiley +1 more source
Genomic and functional divergence analysis of closely related <i>Teseptimavirus</i> phages reveals dual HNH endonuclease positioning and its role in plaque formation. [PDF]
Yang X +6 more
europepmc +1 more source
Archaeal Genes Code for GGDEF Domain Proteins With Diguanylate Cyclase Activity
A biofilm‐like mode of growth is hypothesized to be required for the emergence of cellular life. Occurrence of common biofilm gene products in current Bacteria and Archaea is an indication for their previous presence in the last universal common ancestor LUCA and perhaps even in the first universal common ancestor FUCA.
Roman Sidorov +6 more
wiley +1 more source

